Genetic variation
rs55661361
This variation affects:
Other names:
Overview
rs55661361 is a genetic variant associated with Schizophrenia.
This variant is located on chromosome 11. The variations at position 124744061 are the genetic letters A/A, G/G, C/G, A/G
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs55661361 there are 4 currently known genotypes : A/A, G/G, C/G or A/G
Short Overview
Variant Location
rs55661361 is located on gene in chromsome 11. Use the genome browser to explore the location of rs55661361 and its genetic neighbourhood.
Pharmacogenetics
We do not have any data that links rs55661361 to any drugs.
Diagnostics
rs55661361 is commonly tested together with other variants on the same gene.
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are random changes in the DNA and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Dr. Wallerstorfer
Conditions & Traits of rs55661361
The different genotypes of variant rs55661361 can affect the expression or likelyhood of developing certain traits or conditions. Current research shows that 1 condition and 0 traits are associated with rs55661361. The following table shows the relationship between genotypes and conditions and traits.
Did you know genetic variants affect drugs?
Genetic variants can influence how our body reacts to certain drugs. The presence of specific genetic variants can increase or decrease the efficiency and effectiveness of a drug, impacting how well it works inside our system. Additionally, certain genetic variants can heighten or lessen the toxicity of a drug, thereby affecting the risk of unwanted side effects. They can also alter how a drug is metabolized, which influences the appropriate dosage one should receive.
Dr. Wallerstorfer
Variant Table Legend
Clinical Testing
Scientific Studies
Biological Male Symbol
Biological Female Symbol
Unisex Symbol for both Genders
Variant Classification based on Scientific Studies
Scientific studies classifications aim to uncover how genetic variants function and their roles in diseases, traits, and evolution. Variants are categorized based on their functional impact, such as loss-of-function (reduces gene activity), gain-of-function (increases gene activity), neutral (no significant impact), or evolutionary conservation. This classification uses experimental data, population studies, and computational analyses to understand variant effects. Unlike clinical testing, which focuses on immediate health impacts, scientific studies explore broader genetic mechanisms and long-term implications.
Genotype
A
A
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
G
G
Level of evidence
Increased likelihood
Unisex
3 Sources
Participants: 382126
The genotype with the letters G/G is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
C
G
Level of evidence
Increased likelihood
Unisex
3 Sources
Participants: 382126
The genotype with the letters C/G is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
A
G
Level of evidence
Increased likelihood
Unisex
4 Sources
Participants: 459222
The genotype with the letters A/G is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
A
A
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
G
G
Level of evidence
Increased likelihood
Unisex
3 Sources
Participants: 382126
The genotype with the letters G/G is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
C
G
Level of evidence
Increased likelihood
Unisex
3 Sources
Participants: 382126
The genotype with the letters C/G is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
A
G
Level of evidence
Increased likelihood
Unisex
4 Sources
Participants: 459222
The genotype with the letters A/G is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Pharmacogenetics
The genetic variant rs55661361 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs55661361. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Drugs related to rs55661361
All drugs that are linked to rs55661361 are listed here.
Diagnostics
rs55661361 is commonly tested together with other variants on the same gene.
Related variants
Conditions and traits are often affected by more than one variant. It is important to understand these other factors to get a better understanding of how genetics affect certain conditions and traits. The following grid shows other variants that affect the same conditions and traits as rs55661361.
Genotype Distribution
Knowing your genome can actually tell you a lot about your ancestors.
The prevalence of the different genotypes is based on the native inhabitants of a region. In the map below you see how common each genotype is in the native inhabitants of those regions. Since genetic material is passed down form generation to generation, your DNA shows traces of the geographical origins of your ancestors.
This data is based on “The 1000 Genomes Project” which established one of the most detailed overviews of human genetic variations across the globe. The regions are broadly categorized into five continental groups: Africa, America, Europe, South Asia and East Asia. All continental groups together display the global prevalence. Click through the regions, to learn more about the local prevalence of the possible genotypes.
At present, there is no distribution data available for SNP 55661361. 55661361.
Studies and Sources
All of the resources below examine variant rs
Fernando S Goes, John McGrath, Dimitrios Avramopoulos, Paula Wolyniec, Mehdi Pirooznia, Ingo Ruczinski, Gerald Nestadt, Eimear E Kenny, Vladimir Vacic, Inga Peters, Todd Lencz, Ariel Darvasi, Jennifer G Mulle, Stephen T Warren, Ann E Pulver
Zhiqiang Li, Jianhua Chen, Hao Yu, Lin He, Yifeng Xu, Dai Zhang, Qizhong Yi, Changgui Li, Xingwang Li, Jiawei Shen, Zhijian Song, Weidong Ji, Meng Wang, Juan Zhou, Boyu Chen, Yahui Liu, Jiqiang Wang, Peng Wang, Ping Yang, Qingzhong Wang, Guoyin Feng, Benxiu Liu, Wensheng Sun, Baojie Li, Guang He, Weidong Li, Chunling Wan, Qi Xu, Wenjin Li, Zujia Wen, Ke Liu, Fang Huang, Jue Ji, Stephan Ripke, Weihua Yue, Patrick F Sullivan, Michael C O'Donovan, Yongyong Shi