Overview

rs4291 is a genetic variant.

This variant is located on chromosome 17. The variations at position 63476833 are the genetic letters A/A, C/C, T/T, A/C, A/T, C/T

Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs4291 there are 6 currently known genotypes : A/A, C/C, T/T, A/C, A/T or C/T

Short Overview

Variant Location

rs4291 is located on gene in chromsome 17. Use the genome browser to explore the location of rs4291 and its genetic neighbourhood.

Conditions & Traits

rs4291 affects the following conditions and traits:

There are currently 0 conditions and 0 traits associated with rs4291.

Pathogenicity

rs4291 affects the following conditions:

There are currently 0 conditions associated with rs4291.

Pharmacogenetics

rs4291 affects the following drugs:

Genome Browser

This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.

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Did you know genetic variants affect drugs?

Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.

Dr. Wallerstorfer Dr. Wallerstorfer

Conditions & Traits of rs4291

Current research shows 0 conditions and 0 traits.

Conditions

0

Pharmacogenetics

The genetic variant rs4291 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs4291. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.

Genotype
Level of evidence
Impacts
Summary
AA

Breakdown

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Side Effects

Dosage

No summary available.

more info

AT

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Dosage

No summary available.

more info

TT

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Dosage

No summary available.

more info

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Increased

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No known effect

Genotype
Level of evidence
Impacts
Summary
AA

Breakdown

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Dosage

No summary available.

more info

AT

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No summary available.

more info

TT

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Dosage

No summary available.

more info

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No known effect

Genotype
Level of evidence
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AA

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Dosage

No summary available.

more info

AT

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No summary available.

more info

TT

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No summary available.

more info

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Increased

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No known effect

Genotype
AA
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Side Effects

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Summary

No summary available.

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More info

Genotype
AT
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Summary

No summary available.

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More info

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TT
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Summary

No summary available.

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More info

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Increased

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No known effect

Genotype
AA
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Side Effects

Dosage

Summary

No summary available.

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More info

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AT
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Side Effects

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Summary

No summary available.

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More info

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TT
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Summary

No summary available.

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More info

Legend:

Increased

Decreased

No known effect

Genotype
AA
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
AT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
TT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

Drugs related to rs4291

All drugs that are linked to rs4291 are listed here.

Studies and Sources

All of the resources below examine variant rs4291

Genetic and molecular biology of autism spectrum disorder among Middle East population: a review (3/12/21)

Zahra Rahmani, Mohammad Reza Fayyazi Bordbar, Mohsen Dibaj, Maliheh Alimardani, Meysam Moghbeli

PMC: 7953769
Transmembrane protease serine 2 (TMPRSS2) rs75603675, comorbidity, and sex are the primary predictors of COVID-19 severity (5/30/22)

Gonzalo Villapalos-García, Pablo Zubiaur, Rebeca Rivas-Durán, Pilar Campos-Norte, Cristina Arévalo-Román, Marta Fernández-Rico, Lucio García-Fraile Fraile, Paula Fernández-Campos, Paula Soria-Chacartegui, Sara Fernández de Córdoba-Oñate, Pablo Delgado-Wicke, Elena Fernández-Ruiz, Isidoro González-Álvaro, Jesús Sanz, Francisco Abad-Santos, Ignacio de los Santos

PMC: 9152129
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