Overview

rs35068180 is a genetic variant.

This variant is located on chromosome 11. The variations at position 102845220 are the genetic letters -/-, A/-, A/A

Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs35068180 there are 3 currently known genotypes : -/-, A/- or A/A

Short Overview

Variant Location

rs35068180 is located on gene in chromsome 11. Use the genome browser to explore the location of rs35068180 and its genetic neighbourhood.

Conditions & Traits

rs35068180 affects the following conditions and traits:

There are currently 0 conditions and 0 traits associated with rs35068180.

Pathogenicity

rs35068180 affects the following conditions:

There are currently 0 conditions associated with rs35068180.

Pharmacogenetics

rs35068180 affects the following drugs:

Genome Browser

This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.

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Did you know genetic variants affect drugs?

Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.

Dr. Wallerstorfer Dr. Wallerstorfer

Conditions & Traits of rs35068180

Current research shows 0 conditions and 0 traits.

Conditions

0

Pharmacogenetics

The genetic variant rs35068180 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs35068180. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.

Genotype
Level of evidence
Impacts
Summary
--

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype -/- have increased Drug Effect to CHLORTHALIDONE.

more info

A-

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype A/- have increased Drug Effect to CHLORTHALIDONE.

more info

AA

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

Legend:

Increased

Decreased

No known effect

Genotype
Level of evidence
Impacts
Summary
--

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype -/- have increased Drug Effect to LISINOPRIL.

more info

A-

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype A/- have increased Drug Effect to LISINOPRIL.

more info

AA

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

Legend:

Increased

Decreased

No known effect

Genotype
--
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype -/- have increased Drug Effect to CHLORTHALIDONE.

Level of evidence

More info

Genotype
A-
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype A/- have increased Drug Effect to CHLORTHALIDONE.

Level of evidence

More info

Genotype
AA
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

Genotype
--
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype -/- have increased Drug Effect to LISINOPRIL.

Level of evidence

More info

Genotype
A-
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype A/- have increased Drug Effect to LISINOPRIL.

Level of evidence

More info

Genotype
AA
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

Drugs related to rs35068180

All drugs that are linked to rs35068180 are listed here.

Studies and Sources

All of the resources below examine variant rs35068180

Association of genetic polymorphisms with histological grading of necroinflammation, staging of fibrosis, and liver function in Mexicans with chronic hepatitis C virus infection. (7/14/14)

María Guadalupe Sánchez-Parada, Bertha Adriana Alvarez-Rodríguez, Belinda Claudia Gómez-Meda, Rogelio Troyo-Sanromán, Laura Verónica Sánchez-Orozco, Ana Lourdes Zamora-Perez, Martha Silvia Lucano Landeros, Juan Armendáriz-Borunda

PubMed: 23941979
Matrix Metalloproteinase-3 -1171 5A/6A Polymorphism (rs35068180) is Associated with Risk of Periodontitis. (6/28/16)

Cheng Ding, Xing Chen, Peng-tao Zhang, Jin-ping Huang, Yan Xu, Ning Chen, Liang-jun Zhong

PubMed: 26123623
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