Effect of Variations on the GRIN2B

Variants are common variations in genes that can significantly impact the health and traits of an individual. This section shows all variants that are located on GRIN2B, as well as their associated conditions, traits and drugs.

Did you know that gene anomalies are relatively common?

On average, each person has approximately 100 to 400 genes with variations or mutations (with different genes being affected in different individuals). However, in most cases, the matching gene on the other chromosome in the pair is normal, which helps prevent potential negative effects. In the general population, the likelihood of an individual inheriting two copies of the same abnormal gene—and thus developing a genetic disorder—is very low. However, this risk increases significantly for children of parents who are closely related by blood.

doctor_quote

Dr. Wallerstorfer

Conditions caused and influenced by GRIN2B

Genetic abnormalities can affect the chance of developing a condition by raising or lowering the risk. They can change how a gene works, leading to faulty or missing proteins. However, even with a higher genetic risk, a condition may not develop because factors like environment and lifestyle also have an impact.

Variants located on GRIN2B

The genetic code of a gene is virtually identical between differen people. Only a few individual letters differ from one person to the next.

Did you know genetic variations may affect drugs?

Genetic differences can affect how our body reacts to drugs. Some genes can make a drug work better or worse, and others can change how safe it is or how much of it you need.

doctor_quote

Dr. Wallerstorfer

Pharmacogenetics

Genetic differences can affect how our bodies respond to medications. Some people’s genes can make a drug work better or worse, change how safe it is, or influence how much of the drug they need. These genetic changes can affect how the body processes medicine, like how quickly it is broken down or how it interacts with cells. For example, a genetic difference might cause a person’s body to break down a drug too fast, making it less effective, or too slowly, increasing the risk of side effects. This is why people can have different reactions to the same medication.

rs1806201

Drug
Genotype
Level of evidence
Impacts
Summary

RISPERIDONE

AA

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype A/A have decreased Side Effects to RISPERIDONE.

more info

RISPERIDONE

AG

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype A/G have decreased Side Effects to RISPERIDONE.

more info

RISPERIDONE

GG

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype G/G have increased Side Effects to RISPERIDONE.

more info

Legend:

Increased

Decreased

No known effect

rs1806201

Drug

RISPERIDONE

Genotype
AA
Level of evidence
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype A/A have decreased Side Effects to RISPERIDONE.

More info

Drug

RISPERIDONE

Genotype
AG
Level of evidence
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype A/G have decreased Side Effects to RISPERIDONE.

More info

Drug

RISPERIDONE

Genotype
GG
Level of evidence
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype G/G have increased Side Effects to RISPERIDONE.

More info

Legend:

Increased

Decreased

No known effect

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