This gene is related to these conditions:
Variants are common variations in genes that can significantly impact the health and traits of an individual. This section shows all variants that are located on ALDH2 as well as their associated conditions, traits and drugs.
On average, each person has approximately 100 to 400 genes that are not normal (with different genes being affected in different people). However, usually, the matching gene on the other chromosome within the pair is normal, which helps prevent any potential negative consequences. In the broader population, the odds of someone having two copies of the same abnormal gene (and hence, a genetic disorder) are very low. However, this probability is higher for children whose parents are closely related by blood.
Dr. Wallerstorfer
Genetic abnormalities can significantly influence the likelihood of developing a certain condition, either increasing or decreasing the risk. These mutations can alter gene function, which may result in protein malfunction or a lack of protein production. However, even if a genetic mutation increases the risk, it doesn't necessarily mean the condition will develop as environmental and lifestyle factors also play a role.
Mutations are random changes in the DNA and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Dr. Wallerstorfer
Abnormalities in genes can also have a significant impact on an individual's traits, or physical characteristics. These genetic mutations can affect the way certain traits are expressed by modifying the function of the related genes. However, the manifestation of these traits isn't determined by genetics alone. It's also influenced by a combination of environmental factors and interactions with other genes. Thus, while a gene mutation can potentially influence a trait, it doesn't necessarily dictate its final expression.
A genetic code of a gene usually has many differences in individual genetic letters or tiny pices of the DNA.
Variants can influence how our body reacts to certain drugs. The presence of specific variants can increase or decrease the efficiency and effectiveness of a drug, impacting how well it works inside our system. Additionally, certain variants can heighten or lessen the toxicity of a drug, thereby affecting the risk of unwanted side effects. They can also alter how a drug is metabolized, which influences the appropriate dosage one should receive.
Dr. Wallerstorfer
Variants can significantly influence how our body processes and reacts to drugs. The presence of specific variants can determine the efficiency and effectiveness of a medication, influencing its performance within our system. Additionally, certain variants can modify the drug's toxicity, thereby affecting the likelihood of unwanted side effects. They can also impact how a drug is metabolized, which in turn determines the ideal dosage one should receive. Every individual's response to medication can vary, largely dictated by their genetic makeup. Variations in genes can influence the functions of enzymes, transporters, receptors, and other proteins that interact with drugs. For example, certain genetic variants can alter an enzyme's function, causing it to metabolize a drug too quickly or too slowly. Such variations can either render a treatment ineffective or heighten the risk of side effects.
NALTREXONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect to NALTREXONE.
more info
NALTREXONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to NALTREXONE.
more info
NALTREXONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Drug Effect to NALTREXONE.
more info
Legend:
Increased
Decreased
No known effect
NALTREXONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect to NALTREXONE.
More info
NALTREXONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to NALTREXONE.
More info
NALTREXONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Drug Effect to NALTREXONE.
More info
Legend:
Increased
Decreased
No known effect