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rs1042597

located on UGT1A8 gene

Genotype
CC
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype C/C have increased Side Effects to SIROLIMUS.

Level of evidence

More info

Genotype
CG
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
GG
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

rs1045642

located on ABCB1 gene

Genotype
AA
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
AG
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
GG
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

rs1057868

located on POR gene

Genotype
CC
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
CT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
TT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

rs1042597

located on UGT1A8 gene

Genotype
Level of evidence
Effect
Summary
CC

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype C/C have increased Side Effects to SIROLIMUS.

more info

CG

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

GG

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

Legend:

Increased

Decreased

No known effect

rs1045642

located on ABCB1 gene

Genotype
Level of evidence
Effect
Summary
AA

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

AG

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

GG

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

Legend:

Increased

Decreased

No known effect

rs1057868

located on POR gene

Genotype
Level of evidence
Effect
Summary
CC

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

CT

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

TT

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

Legend:

Increased

Decreased

No known effect

Variants that influence SIROLIMUS

Genes that influence SIROLIMUS

Conditions treated by SIROLIMUS

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