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Variants that influence Preeclampsia based on Clinical Testing
Clinical testing classifications are designed to help doctors understand how genetic changes, known as variants, might affect a person’s health and guide medical decisions. Variants are labeled as Disease Causing (harmful), likely Disease Causing, Unknown Effect (unknown impact), Likely No Effect (likely not harmful), and No Effect (not harmful). This classification relies on a mix of family history, lab tests, and computer predictions to determine the impact of variants.
Variants that Affect Both Biological Males and Females
Genotype
G
G
Level of evidence
No Effect
Unisex
1 Sources
Participants: 0
The genotype with the letters G/G is thought to have no effect on your disease risk. Carriers of this genetic result are usually not at risk of developing the disease.
Genotype
A
G
Level of evidence
Unknown effect
Unisex
1 Sources
Participants: 0
The genotype with the letters A/G has an unknown effect on your disease risk. This means that the scientific evidence is still somewhat unclear about its effect.
Genotype
A
A
Level of evidence
Unknown effect
Unisex
1 Sources
Participants: 0
The genotype with the letters A/A has an unknown effect on your disease risk. This means that the scientific evidence is still somewhat unclear about its effect.
Genotype
G
G
Level of evidence
No Effect
Unisex
1 Sources
Participants: 0
The genotype with the letters G/G is thought to have no effect on your disease risk. Carriers of this genetic result are usually not at risk of developing the disease.
Genotype
A
G
Level of evidence
Unknown effect
Unisex
1 Sources
Participants: 0
The genotype with the letters A/G has an unknown effect on your disease risk. This means that the scientific evidence is still somewhat unclear about its effect.
Genotype
A
A
Level of evidence
Unknown effect
Unisex
1 Sources
Participants: 0
The genotype with the letters A/A has an unknown effect on your disease risk. This means that the scientific evidence is still somewhat unclear about its effect.
Variants that influence Preeclampsia based on Scientific Studies
Scientific studies classifications aim to uncover how genetic variants function and their roles in diseases, traits, and evolution. Variants are categorized based on their functional impact, such as loss-of-function (reduces gene activity), gain-of-function (increases gene activity), neutral (no significant impact), or evolutionary conservation. This classification uses experimental data, population studies, and computational analyses to understand variant effects. Unlike clinical testing, which focuses on immediate health impacts, scientific studies explore broader genetic mechanisms and long-term implications.
Variants that Affect Both Biological Males and Females
Genotype
T
T
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
T
C
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
C
C
Level of evidence
Increased likelihood
Unisex
2 Sources
Participants: 760882
The genotype with the letters C/C is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
T
T
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
T
C
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
C
C
Level of evidence
Increased likelihood
Unisex
2 Sources
Participants: 760882
The genotype with the letters C/C is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
G
G
Level of evidence
Increased likelihood
Unisex
1 Sources
Participants: 167234
The genotype with the letters G/G is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
G
A
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
A
A
Level of evidence
Reduced likelihood
Unisex
1 Sources
Participants: 593648
The genotype with the letters A/A is considered protective. Carriers of this genetic result are at reduced risk of developing the disease.
Genotype
G
G
Level of evidence
Increased likelihood
Unisex
1 Sources
Participants: 167234
The genotype with the letters G/G is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
G
A
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
A
A
Level of evidence
Reduced likelihood
Unisex
1 Sources
Participants: 593648
The genotype with the letters A/A is considered protective. Carriers of this genetic result are at reduced risk of developing the disease.
Genotype
G
G
Level of evidence
Increased likelihood
Unisex
1 Sources
Participants: 167234
The genotype with the letters G/G is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
G
C
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
C
C
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
G
G
Level of evidence
Increased likelihood
Unisex
1 Sources
Participants: 167234
The genotype with the letters G/G is considered a risk factor for developing the disease. Carriers of this genetic result are at increased risk of developing the disease.
Genotype
G
C
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data
Genotype
C
C
Level of evidence
No Effect
Unisex
0 Sources
Participants: 0
No available data