Overview

rs895819 is a genetic variant.

This variant is located on chromosome 19. The variations at position 13836478 are the genetic letters A/A, C/C, G/G, T/T, A/C, C/G, G/T, A/T, A/G, C/T

Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs895819 there are 10 currently known genotypes : A/A, C/C, G/G, T/T, A/C, C/G, G/T, A/T, A/G or C/T

Short Overview

Variant Location

rs895819 is located on gene in chromsome 19. Use the genome browser to explore the location of rs895819 and its genetic neighbourhood.

Conditions & Traits

rs895819 affects the following conditions and traits:

There are currently 0 conditions and 0 traits associated with rs895819.

Pathogenicity

rs895819 affects the following conditions:

There are currently 0 conditions associated with rs895819.

Pharmacogenetics

rs895819 affects the following drugs:

Genome Browser

This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.

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Did you know genetic variants affect drugs?

Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.

Dr. Wallerstorfer Dr. Wallerstorfer

Conditions & Traits of rs895819

Current research shows 0 conditions and 0 traits.

Conditions

0

Pharmacogenetics

The genetic variant rs895819 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs895819. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.

Genotype
Level of evidence
Impacts
Summary
CC

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype C/C have increased Side Effects to CAPECITABINE.

more info

CT

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype C/T have increased Side Effects to CAPECITABINE.

more info

TT

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype T/T have decreased Side Effects to CAPECITABINE.

more info

Legend:

Increased

Decreased

No known effect

Genotype
Level of evidence
Impacts
Summary
CC

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype C/C have increased Side Effects to FLUOROURACIL.

more info

CT

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype C/T have increased Side Effects to FLUOROURACIL.

more info

TT

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype T/T have decreased Side Effects to FLUOROURACIL.

more info

Legend:

Increased

Decreased

No known effect

Genotype
CC
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype C/C have increased Side Effects to CAPECITABINE.

Level of evidence

More info

Genotype
CT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype C/T have increased Side Effects to CAPECITABINE.

Level of evidence

More info

Genotype
TT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype T/T have decreased Side Effects to CAPECITABINE.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

Genotype
CC
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype C/C have increased Side Effects to FLUOROURACIL.

Level of evidence

More info

Genotype
CT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype C/T have increased Side Effects to FLUOROURACIL.

Level of evidence

More info

Genotype
TT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype T/T have decreased Side Effects to FLUOROURACIL.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

Drugs related to rs895819

All drugs that are linked to rs895819 are listed here.

Studies and Sources

All of the resources below examine variant rs895819

The Single-Nucleotide Polymorphism of miR-27a rs895819 and the Expression of miR-27a in Helicobacter pylori-Related Diseases and the Correlation with the Traditional Chinese Medicine Syndrome

Ling Zhang, Meng-Xin Huang, Dan-Yan Li, Yun-Zhan Zhang, Shao-Yang Lan, Qi Luo, Yun-Kai Dai, Yun-Bo Wu, Jin-Tong Ye, Wei-Jing Chen, Ru-Liu Li, Ling Hu

PMC: 8941553
Single-nucleotide polymorphisms as important risk factors of diabetes among Middle East population (4/2/22)

Iman Akhlaghipour, Amir Reza Bina, Mohammad Reza Mogharrabi, Ali Fanoodi, Amir Reza Ebrahimian, Soroush Khojasteh Kaffash, Atefeh Babazadeh Baghan, Mohammad Erfan Khorashadizadeh, Negin Taghehchian, Meysam Moghbeli

PMC: 8976361
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