Overview
rs8099917 is a genetic variant.
This variant is located on chromosome 19. The variations at position 39252525 are the genetic letters G/G, T/T, G/T
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs8099917 there are 3 currently known genotypes : G/G, T/T or G/T
Short Overview
Variant Location
rs8099917 is located on gene in chromsome 19. Use the genome browser to explore the location of rs8099917 and its genetic neighbourhood.
Conditions & Traits
rs8099917 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs8099917.
Pathogenicity
rs8099917 affects the following conditions:
There are currently 0 conditions associated with rs8099917.
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Conditions & Traits of rs8099917
Current research shows 0 conditions and 0 traits.
Conditions
0Pharmacogenetics
The genetic variant rs8099917 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs8099917. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to LEDIPASVIR.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/T have decreased Drug Effect to LEDIPASVIR.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Drug Effect to LEDIPASVIR.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to RIBAVIRIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/T have decreased Drug Effect to RIBAVIRIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Drug Effect to RIBAVIRIN.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to SOFOSBUVIR.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/T have decreased Drug Effect to SOFOSBUVIR.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Drug Effect to SOFOSBUVIR.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to LEDIPASVIR.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/T have decreased Drug Effect to LEDIPASVIR.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Drug Effect to LEDIPASVIR.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to RIBAVIRIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/T have decreased Drug Effect to RIBAVIRIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Drug Effect to RIBAVIRIN.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to SOFOSBUVIR.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/T have decreased Drug Effect to SOFOSBUVIR.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Drug Effect to SOFOSBUVIR.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Drugs related to rs8099917
All drugs that are linked to rs8099917 are listed here.
Studies and Sources
All of the resources below examine variant rs8099917
Junbo Tian, Jing Zhang, Zengguang Yang, Shuaisheng Feng, Shujuan Li, Shiqi Ren, Jianxiang Shi, Xinyue Hou, Xia Xue, Bei Yang, Hongen Xu, Jiancheng Guo
Jessica Cusato, Lucio Boglione, Amedeo De Nicolò, Gian Paolo Caviglia, Simone Mornese Pinna, Alessia Ciancio, Giulia Troshina, Antonina Smedile, Miriam Antonucci, Valeria Avataneo, Alice Palermiti, Jacopo Mula, Alessandra Manca, Giuseppe Cariti, Marco Cantù, Giorgio Maria Saracco, Giovanni Di Perri, Antonio D’Avolio
Linjie Weng, Guoqing Huang, Luping Gong, Jialu Xu, Yushan Mao, Yan Li, Mingcai Li