Overview
rs727479 is a genetic variant.
This variant is located on chromosome 15. The variations at position 51242350 are the genetic letters A/A, C/C, G/G, T/T, A/C, C/G, G/T, A/T, A/G, C/T
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs727479 there are 10 currently known genotypes : A/A, C/C, G/G, T/T, A/C, C/G, G/T, A/T, A/G or C/T
Short Overview
Variant Location
rs727479 is located on gene in chromsome 15. Use the genome browser to explore the location of rs727479 and its genetic neighbourhood.
Conditions & Traits
rs727479 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs727479.
Pathogenicity
rs727479 affects the following conditions:
There are currently 0 conditions associated with rs727479.
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Conditions & Traits of rs727479
Current research shows 0 conditions and 0 traits.
Conditions
0Pharmacogenetics
The genetic variant rs727479 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs727479. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to ANASTROZOLE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/C have increased Drug Effect to ANASTROZOLE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Drug Effect to ANASTROZOLE.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to ANASTROZOLE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/C have increased Drug Effect to ANASTROZOLE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Drug Effect to ANASTROZOLE.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Drugs related to rs727479
All drugs that are linked to rs727479 are listed here.
Studies and Sources
All of the resources below examine variant rs727479
Dylan M. Glubb, Tracy A. O'Mara, Jannah Shamsani, Amanda B. Spurdle
Xiying Shao, Lei Luo, Yong Guo, Xiaohong Xu, Dehou Deng, Jianguo Feng, Yuheng Ding, Hanzhou Mou, Ping Huang, Lei Shi, Yuan Huang, Weiwu Ye, Caijin Lou, Zhanhong Chen, Yabing Zheng, Xiaojia Wang
Anna L Eriksson, John R B Perry, Andrea D Coviello, Graciela E Delgado, Luigi Ferrucci, Andrew R Hoffman, Ilpo T Huhtaniemi, M Arfan Ikram, Magnus K Karlsson, Marcus E Kleber, Gail A Laughlin, Yongmei Liu, Mattias Lorentzon, Kathryn L Lunetta, Dan Mellström, Joanne M Murabito, Anna Murray, Maria Nethander, Carrie M Nielson, Inga Prokopenko, Stephen R Pye, Leslie J Raffel, Fernando Rivadeneira, Priya Srikanth, Lisette Stolk, Alexander Teumer, Thomas G Travison, André G Uitterlinden, Dhananjay Vaidya, Dirk Vanderschueren, Joseph M Zmuda, Winfried März, Eric S Orwoll, Pamela Ouyang, Liesbeth Vandenput, Frederick C W Wu, Frank H de Jong, Shalender Bhasin, Douglas P Kiel, Claes Ohlsson