Overview
rs699947 is a genetic variant.
This variant is located on chromosome 6. The variations at position 43768652 are the genetic letters A/A, C/C, T/T, A/C, A/T, C/T
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs699947 there are 6 currently known genotypes : A/A, C/C, T/T, A/C, A/T or C/T
Short Overview
Variant Location
rs699947 is located on gene in chromsome 6. Use the genome browser to explore the location of rs699947 and its genetic neighbourhood.
Conditions & Traits
rs699947 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs699947.
Pathogenicity
rs699947 affects the following conditions:
There are currently 0 conditions associated with rs699947.
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Conditions & Traits of rs699947
Current research shows 0 conditions and 0 traits.
Conditions
0Pharmacogenetics
The genetic variant rs699947 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs699947. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/C have decreased Drug Effect to CAPECITABINE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Drug Effect to CAPECITABINE.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to DOCETAXEL.
more info
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have decreased Drug Effect to DOCETAXEL.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/C have decreased Drug Effect to FLUOROURACIL.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Drug Effect to FLUOROURACIL.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/C have decreased Drug Effect to CAPECITABINE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Drug Effect to CAPECITABINE.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to DOCETAXEL.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have decreased Drug Effect to DOCETAXEL.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/C have decreased Drug Effect to FLUOROURACIL.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Drug Effect to FLUOROURACIL.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Drugs related to rs699947
All drugs that are linked to rs699947 are listed here.
Studies and Sources
All of the resources below examine variant rs699947
Shan Zhang, Yujia Lu, Wei Shi, Yi Ren, Kaihui Xiao, Wei Chen, Li Li, Jingjie Zhao
Laura Filonzi, Serafina Perrone, Maria Luisa Tataranno, Cinzia Magnani, Harold Dadomo, Anthea Bottoni, Marina Vaghi, Francesco Nonnis Marzano
Manav Gandhi, Viral Bakhai, Jash Trivedi, Adarsh Mishra, Fernando De Andrés, Adrián LLerena, Rohit Sharma, Sujit Nair