Overview

rs6686529 is a genetic variant on gene KCNK2.

This variant is located on chromosome 1. The variations at position 215236763 are the genetic letters C/C, G/G, C/G, G/T

Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs6686529 there are 4 currently known genotypes : C/C, G/G, C/G or G/T

Short Overview

Variant Location

rs6686529 is located on gene KCNK2 in chromsome 1. Use the genome browser to explore the location of rs6686529 and its genetic neighbourhood.

Conditions & Traits

rs6686529 affects the following conditions and traits:

There are currently 0 conditions and 0 traits associated with rs6686529.

Pathogenicity

rs6686529 affects the following conditions:

There are currently 0 conditions associated with rs6686529.

Pharmacogenetics

rs6686529 affects the following drugs:

Genome Browser

This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs on gene KCNK2. Explore more variants and their effects on the body by browsing left and right along the DNA strand.

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Did you know genetic variants affect drugs?

Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.

Dr. Wallerstorfer Dr. Wallerstorfer

Conditions & Traits of rs6686529

Current research shows 0 conditions and 0 traits.

Conditions

0

Pharmacogenetics

The genetic variant rs6686529 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs6686529. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.

Genotype
Level of evidence
Impacts
Summary
CC

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

CG

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype C/G have increased Drug Effect to SEVOFLURANE.

more info

GG

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype G/G have decreased Drug Effect to SEVOFLURANE.

more info

Legend:

Increased

Decreased

No known effect

Genotype
CC
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
CG
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype C/G have increased Drug Effect to SEVOFLURANE.

Level of evidence

More info

Genotype
GG
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype G/G have decreased Drug Effect to SEVOFLURANE.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

Drugs related to rs6686529

All drugs that are linked to rs6686529 are listed here.

Studies and Sources

All of the resources below examine variant rs6686529

Study of the Association of Single Nucleotide Polymorphisms in Candidate Genes With Sevoflurane. (1/5/23)

Shuai Zhao, Shiqian Huang, Qi Zhong, Linlin Han, Yafeng Wang, Feng Xu, Lulin Ma, Yuanyuan Ding, Leiming Xia, Xiangdong Chen

PubMed: 35943164
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