Overview

rs6494223 is a genetic variant.

This variant is located on chromosome 15. The variations at position 32104256 are the genetic letters C/C, T/T, C/T

Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs6494223 there are 3 currently known genotypes : C/C, T/T or C/T

Short Overview

Variant Location

rs6494223 is located on gene in chromsome 15. Use the genome browser to explore the location of rs6494223 and its genetic neighbourhood.

Conditions & Traits

rs6494223 affects the following conditions and traits:

There are currently 0 conditions and 0 traits associated with rs6494223.

Pathogenicity

rs6494223 affects the following conditions:

There are currently 0 conditions associated with rs6494223.

Pharmacogenetics

rs6494223 affects the following drugs:

Genome Browser

This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.

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Did you know genetic variants affect drugs?

Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.

Dr. Wallerstorfer Dr. Wallerstorfer

Conditions & Traits of rs6494223

Current research shows 0 conditions and 0 traits.

Conditions

0

Pharmacogenetics

The genetic variant rs6494223 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs6494223. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.

Genotype
Level of evidence
Impacts
Summary
CC

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype C/C have decreased Drug Effect to RIVASTIGMINE.

more info

CT

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

TT

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype T/T have increased Drug Effect to RIVASTIGMINE.

more info

Legend:

Increased

Decreased

No known effect

Genotype
CC
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype C/C have decreased Drug Effect to RIVASTIGMINE.

Level of evidence

More info

Genotype
CT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
TT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype T/T have increased Drug Effect to RIVASTIGMINE.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

Drugs related to rs6494223

All drugs that are linked to rs6494223 are listed here.

Studies and Sources

All of the resources below examine variant rs6494223

Meta-analyses of 10 polymorphisms associated with the risk of schizophrenia (September 2014)

DONGJUN DAI, YUNLIANG WANG, JIAOJIAO YUAN, XINGYU ZHOU, DANJIE JIANG, JINFENG LI, YUZHENG ZHANG, HONGLEI YIN, SHIWEI DUAN

PMC: 4106624
Genetic polymorphism analysis of patients with primary hyperhidrosis

Bryce C Simes, Joshua P Moore, Terry C Brown, Tyler J Rushforth, Angela L Bookout, Chante L Richardson

PMC: 6187922
Genes Involved in Neurodevelopment, Neuroplasticity and Major Depression: No Association for CACNA1C, CHRNA7 and MAPK1 (August 2019)

Marco Calabrò, Laura Mandelli, Concetta Crisafulli, Soo-Jung Lee, Tae-Youn Jun, Sheng-Min Wang, Ashwin A. Patkar, Prakash S. Masand, Changsu Han, Chi-Un Pae, Alessandro Serretti

PMC: 6705106
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