Overview
rs639174 is a genetic variant.
This variant is located on chromosome 5. The variations at position 31433540 are the genetic letters C/C, T/T, C/T
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs639174 there are 3 currently known genotypes : C/C, T/T or C/T
Short Overview
Variant Location
rs639174 is located on gene in chromsome 5. Use the genome browser to explore the location of rs639174 and its genetic neighbourhood.
Conditions & Traits
rs639174 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs639174.
Pathogenicity
rs639174 affects the following conditions:
There are currently 0 conditions associated with rs639174.
Pharmacogenetics
rs639174 affects the following drugs:
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Conditions & Traits of rs639174
Current research shows 0 conditions and 0 traits.
Conditions
0Pharmacogenetics
The genetic variant rs639174 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs639174. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have decreased Side Effects to CYCLOPHOSPHAMIDE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Side Effects to CYCLOPHOSPHAMIDE.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have decreased Side Effects to CYTARABINE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Side Effects to CYTARABINE.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have decreased Side Effects to DAUNORUBICIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Side Effects to DAUNORUBICIN.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have decreased Side Effects to CYCLOPHOSPHAMIDE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Side Effects to CYCLOPHOSPHAMIDE.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have decreased Side Effects to CYTARABINE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Side Effects to CYTARABINE.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have decreased Side Effects to DAUNORUBICIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Side Effects to DAUNORUBICIN.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Drugs related to rs639174
All drugs that are linked to rs639174 are listed here.
Studies and Sources
All of the resources below examine variant rs639174
Lila E. Mullany, Jennifer S. Herrick, Roger K. Wolff, Matthew F. Buas, Martha L. Slattery
Simone Detassis, Margherita Grasso, Valerio Del Vescovo, Michela A. Denti
Sonja Pavlovic, Nikola Kotur, Biljana Stankovic, Branka Zukic, Vladimir Gasic, Lidija Dokmanovic