Overview

rs577001 is a genetic variant.

This variant is located on chromosome 6. The variations at position 149325172 are the genetic letters C/C, T/T, C/T

Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs577001 there are 3 currently known genotypes : C/C, T/T or C/T

Short Overview

Variant Location

rs577001 is located on gene in chromsome 6. Use the genome browser to explore the location of rs577001 and its genetic neighbourhood.

Conditions & Traits

rs577001 affects the following conditions and traits:

There are currently 0 conditions and 0 traits associated with rs577001.

Pathogenicity

rs577001 affects the following conditions:

There are currently 0 conditions associated with rs577001.

Pharmacogenetics

rs577001 affects the following drugs:

Genome Browser

This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.

Loading Genome Browser...

Did you know genetic variants affect drugs?

Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.

Dr. Wallerstorfer Dr. Wallerstorfer

Conditions & Traits of rs577001

Current research shows 0 conditions and 0 traits.

Conditions

0

Pharmacogenetics

The genetic variant rs577001 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs577001. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.

Genotype
Level of evidence
Impacts
Summary
CC

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype C/C have increased Side Effects to GEFITINIB.

more info

CT

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

TT

Breakdown

Drug Effect

Side Effects

Dosage

No summary available.

more info

Legend:

Increased

Decreased

No known effect

Genotype
CC
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype C/C have increased Side Effects to GEFITINIB.

Level of evidence

More info

Genotype
CT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
TT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

Drugs related to rs577001

All drugs that are linked to rs577001 are listed here.

Studies and Sources

All of the resources below examine variant rs577001

Association of small ubiquitin-like modifier 4 (SUMO4) variant, located in IDDM5 locus, with type 2 diabetes in the Japanese population. (7/18/07)

Shinsuke Noso, Tomomi Fujisawa, Yumiko Kawabata, Katsuaki Asano, Yoshihisa Hiromine, Aya Fukai, Toshio Ogihara, Hiroshi Ikegami

PubMed: 17374705
DISCLAIMER: The materials present on Genopedia.com, such as text, images, graphics, among other items (“Content”), are shared purely for informational reasons. This content should not replace professional health advice, medical diagnoses, or treatment procedures. Whenever you have health concerns or questions, it’s always recommended to engage with your doctor or another appropriate healthcare provider. If you read something on the Genopedia.com site, do not neglect professional medical counsel or delay in obtaining it. In case you believe you’re dealing with a medical crisis, get in touch with your medical professional or call emergency without delay. Genopedia.com doesn’t advocate for any particular medical tests, healthcare providers, products, methods, beliefs, or other data that could be discussed on the site. Please also note that the content, originally written in English and in part created with the help of artificial intelligence, is provided without any warranty, and any reliance on information offered by Genopedia.com, its staff, contributors invited by Genopedia.com, or site users is entirely at your own risk.
Genopedia © 2026 all rights reserved