Overview
rs4240803 is a genetic variant.
This variant is located on chromosome 16. The variations at position 87855597 are the genetic letters A/A, G/G, A/G
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs4240803 there are 3 currently known genotypes : A/A, G/G or A/G
Short Overview
Variant Location
rs4240803 is located on gene in chromsome 16. Use the genome browser to explore the location of rs4240803 and its genetic neighbourhood.
Conditions & Traits
rs4240803 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs4240803.
Pathogenicity
rs4240803 affects the following conditions:
There are currently 0 conditions associated with rs4240803.
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Conditions & Traits of rs4240803
Current research shows 0 conditions and 0 traits.
Conditions
0Pharmacogenetics
The genetic variant rs4240803 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs4240803. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect and increased Dosage to GABAPENTIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Drug Effect, increased Dosage and increased Side Effects to GABAPENTIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect, decreased Dosage and decreased Side Effects to GABAPENTIN.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Side Effects to MELPHALAN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Side Effects to MELPHALAN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to MELPHALAN.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect to PREGABALIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Drug Effect and increased Side Effects to PREGABALIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Drug Effect and decreased Side Effects to PREGABALIN.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Drug Effect and increased Dosage to GABAPENTIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Drug Effect, increased Dosage and increased Side Effects to GABAPENTIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect, decreased Dosage and decreased Side Effects to GABAPENTIN.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Side Effects to MELPHALAN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Side Effects to MELPHALAN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to MELPHALAN.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Drug Effect to PREGABALIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Drug Effect and increased Side Effects to PREGABALIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Drug Effect and decreased Side Effects to PREGABALIN.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Drugs related to rs4240803
All drugs that are linked to rs4240803 are listed here.
Studies and Sources
All of the resources below examine variant rs4240803
B.M. Anderson, N.C. Schnetz-Boutaud, J. Bartlett, A.M. Wotawa, H.H. Wright, R.K. Abramson, M.L. Cuccaro, J.R. Gilbert, M.A. Pericak-Vance, J.L. Haines
Jennifer L. Giglia, Marquitta J. White, Andrew J. Hart, Juan J. Toro, César O. Freytes, Cherish C. Holt, Ying Cai, Scott M. Williams, Stephen J. Brandt
Vittorio Simeon, Katia Todoerti, Francesco La Rocca, Antonella Caivano, Stefania Trino, Marta Lionetti, Luca Agnelli, Luciana De Luca, Ilaria Laurenzana, Antonino Neri, Pellegrino Musto