Overview

rs3888190 is a genetic variant.

This variant is located on chromosome 16. The variations at position 28878165 are the genetic letters A/A, C/C, G/G, T/T, A/C, C/G, G/T, A/T, A/G, C/T

Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs3888190 there are 10 currently known genotypes : A/A, C/C, G/G, T/T, A/C, C/G, G/T, A/T, A/G or C/T

Short Overview

Variant Location

rs3888190 is located on gene in chromsome 16. Use the genome browser to explore the location of rs3888190 and its genetic neighbourhood.

Conditions & Traits

rs3888190 affects the following conditions and traits:

There are currently 0 conditions and 0 traits associated with rs3888190.

Pathogenicity

rs3888190 affects the following conditions:

There are currently 0 conditions associated with rs3888190.

Genome Browser

This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.

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Did you know genetic variants affect drugs?

Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.

Dr. Wallerstorfer Dr. Wallerstorfer

Conditions & Traits of rs3888190

Current research shows 0 conditions and 0 traits.

Conditions

0

Pharmacogenetics

The genetic variant rs3888190 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs3888190. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.

Genotype
Level of evidence
Impacts
Summary
AA

Breakdown

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Side Effects

Dosage

No summary available.

more info

AC

Breakdown

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Dosage

No summary available.

more info

CC

Breakdown

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Dosage

No summary available.

more info

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Increased

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No known effect

Genotype
Level of evidence
Impacts
Summary
AA

Breakdown

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Dosage

No summary available.

more info

AC

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No summary available.

more info

CC

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Drug Effect

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Dosage

No summary available.

more info

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Decreased

No known effect

Genotype
Level of evidence
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Summary
AA

Breakdown

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Dosage

No summary available.

more info

AC

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No summary available.

more info

CC

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No summary available.

more info

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No known effect

Genotype
AA
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Drug Effect

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Dosage

Summary

No summary available.

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More info

Genotype
AC
Impacts

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Side Effects

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Summary

No summary available.

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More info

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CC
Impacts

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Summary

No summary available.

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More info

Legend:

Increased

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No known effect

Genotype
AA
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Drug Effect

Side Effects

Dosage

Summary

No summary available.

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More info

Genotype
AC
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Dosage

Summary

No summary available.

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More info

Genotype
CC
Impacts

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Summary

No summary available.

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More info

Legend:

Increased

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No known effect

Genotype
AA
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
AC
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Genotype
CC
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

No summary available.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

Drugs related to rs3888190

All drugs that are linked to rs3888190 are listed here.

Studies and Sources

All of the resources below examine variant rs3888190

The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells. (4/5/12)

Sabrina Prudente, Eleonora Morini, Jay Larmon, Francesco Andreozzi, Natalia Di Pietro, Angela Nigro, Ernest V Gervino, Gaia Chiara Mannino, Simonetta Bacci, Thomas H Hauser, Emanuele Bellacchio, Gloria Formoso, Fabio Pellegrini, Vittoria Proto, Claudia Menzaghi, Lucia Frittitta, Assunta Pandolfi, Giorgio Sesti, Alessandro Doria, Vincenzo Trischitta

PubMed: 21907990
Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci. (August 2016)

Samuel E Jones, Jessica Tyrrell, Andrew R Wood, Robin N Beaumont, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Youna Hu, Maris Teder-Laving, Caroline Hayward, Till Roenneberg, James F Wilson, Fabiola Del Greco, Andrew A Hicks, Chol Shin, Chang-Ho Yun, Seung Ku Lee, Andres Metspalu, Enda M Byrne, Philip R Gehrman, Henning Tiemeier, Karla V Allebrandt, Rachel M Freathy, Anna Murray, David A Hinds, Timothy M Frayling, Michael N Weedon

PubMed: 27494321
Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI. (11/21/19)

Claudia Pisanu, Michael J Williams, Diana M Ciuculete, Gaia Olivo, Maria Del Zompo, Alessio Squassina, Helgi B Schiöth

PubMed: 31754094
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