Overview

rs3832043 is a genetic variant.

This variant is located on chromosome 2. The variations at position 233671817 are the genetic letters -/-, T/-, T/T

Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs3832043 there are 3 currently known genotypes : -/-, T/- or T/T

Short Overview

Variant Location

rs3832043 is located on gene in chromsome 2. Use the genome browser to explore the location of rs3832043 and its genetic neighbourhood.

Conditions & Traits

rs3832043 affects the following conditions and traits:

There are currently 0 conditions and 0 traits associated with rs3832043.

Pathogenicity

rs3832043 affects the following conditions:

There are currently 0 conditions associated with rs3832043.

Pharmacogenetics

rs3832043 affects the following drugs:

Genome Browser

This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.

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Did you know genetic variants affect drugs?

Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.

Dr. Wallerstorfer Dr. Wallerstorfer

Conditions & Traits of rs3832043

Current research shows 0 conditions and 0 traits.

Conditions

0

Pharmacogenetics

The genetic variant rs3832043 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs3832043. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.

Genotype
Level of evidence
Impacts
Summary
--

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype -/- have decreased Breakdown to MYCOPHENOLATE MOFETIL.

more info

T-

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype T/- have decreased Breakdown to MYCOPHENOLATE MOFETIL.

more info

TT

Breakdown

Drug Effect

Side Effects

Dosage

Individuals with the genotype T/T have decreased Breakdown to MYCOPHENOLATE MOFETIL.

more info

Legend:

Increased

Decreased

No known effect

Genotype
--
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype -/- have decreased Breakdown to MYCOPHENOLATE MOFETIL.

Level of evidence

More info

Genotype
T-
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype T/- have decreased Breakdown to MYCOPHENOLATE MOFETIL.

Level of evidence

More info

Genotype
TT
Impacts

Breakdown

Drug Effect

Side Effects

Dosage

Summary

Individuals with the genotype T/T have decreased Breakdown to MYCOPHENOLATE MOFETIL.

Level of evidence

More info

Legend:

Increased

Decreased

No known effect

Drugs related to rs3832043

All drugs that are linked to rs3832043 are listed here.

Studies and Sources

All of the resources below examine variant rs3832043

Lack of association between common polymorphisms in UGT1A9 and gene expression and activity. (1/3/08)

Jacqueline Ramírez, Wanqing Liu, Snezana Mirkov, Apurva A Desai, Peixian Chen, Soma Das, Federico Innocenti, Mark J Ratain

PubMed: 17761781
Pharmacogenetics and pharmacokinetics modeling of unexpected and extremely severe toxicities after sorafenib intake. (1/11/21)

Hai le Ba, Litaty Mbatchi, Florence Gattacceca, Alexandre Evrard, Bruno Lacarelle, Benoit Blanchet, Joseph Ciccolini, Sébastien Salas

PubMed: 31967518
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