Overview
rs3761422 is a genetic variant.
This variant is located on chromosome 22. The variations at position 24430704 are the genetic letters A/A, C/C, T/T, A/C, A/T, C/T
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs3761422 there are 6 currently known genotypes : A/A, C/C, T/T, A/C, A/T or C/T
Short Overview
Variant Location
rs3761422 is located on gene in chromsome 22. Use the genome browser to explore the location of rs3761422 and its genetic neighbourhood.
Conditions & Traits
rs3761422 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs3761422.
Pathogenicity
rs3761422 affects the following conditions:
There are currently 0 conditions associated with rs3761422.
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Conditions & Traits of rs3761422
Current research shows 0 conditions and 0 traits.
Conditions
0Pharmacogenetics
The genetic variant rs3761422 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs3761422. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Genotype
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Dosage
No summary available.
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No summary available.
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No known effect
Genotype
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Summary
Breakdown
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Dosage
Individuals with the genotype C/C have decreased Side Effects to METHOTREXATE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have increased Side Effects to METHOTREXATE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Side Effects to METHOTREXATE.
more info
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No known effect
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No summary available.
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No summary available.
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Summary
No summary available.
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More info
Legend:
Increased
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No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have decreased Side Effects to METHOTREXATE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have increased Side Effects to METHOTREXATE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Side Effects to METHOTREXATE.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Drugs related to rs3761422
All drugs that are linked to rs3761422 are listed here.
Studies and Sources
All of the resources below examine variant rs3761422
Debleena Guin, Manish Kumar Mishra, Puneet Talwar, Chitra Rawat, Suman S. Kushwaha, Shrikant Kukreti, Ritushree Kukreti
N. F. Banks, P. M. Tomko, R. J. Colquhoun, T. W. D. Muddle, S. R. Emerson, N. D. M. Jenkins
Artemii Tretiakov, Alena Malakhova, Elena Naumova, Olga Rudko, Eugene Klimov