Overview
rs2514218 is a genetic variant.
This variant is located on chromosome 11. The variations at position 113522272 are the genetic letters A/A, C/C, G/G, T/T, A/C, C/G, G/T, A/T, A/G, C/T
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs2514218 there are 10 currently known genotypes : A/A, C/C, G/G, T/T, A/C, C/G, G/T, A/T, A/G or C/T
Short Overview
Variant Location
rs2514218 is located on gene in chromsome 11. Use the genome browser to explore the location of rs2514218 and its genetic neighbourhood.
Conditions & Traits
rs2514218 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs2514218.
Pathogenicity
rs2514218 affects the following conditions:
There are currently 0 conditions associated with rs2514218.
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Conditions & Traits of rs2514218
Current research shows 0 conditions and 0 traits.
Conditions
0Pharmacogenetics
The genetic variant rs2514218 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs2514218. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Drug Effect and increased Side Effects to ARIPIPRAZOLE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have decreased Drug Effect to ARIPIPRAZOLE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have decreased Drug Effect to ARIPIPRAZOLE.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Drug Effect to RISPERIDONE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have decreased Drug Effect to RISPERIDONE.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have decreased Drug Effect to RISPERIDONE.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Drug Effect and increased Side Effects to ARIPIPRAZOLE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have decreased Drug Effect to ARIPIPRAZOLE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have decreased Drug Effect to ARIPIPRAZOLE.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Drug Effect to RISPERIDONE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have decreased Drug Effect to RISPERIDONE.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have decreased Drug Effect to RISPERIDONE.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Drugs related to rs2514218
All drugs that are linked to rs2514218 are listed here.
Studies and Sources
All of the resources below examine variant rs2514218
Shimeng Jiao, Ting Cao, Hualin Cai
Joseph D. Deak, Daniel F. Levey, Frank R. Wendt, Hang Zhou, Marco Galimberti, Henry R. Kranzler, J. Michael Gaziano, Murray B. Stein, Renato Polimanti, Joel Gelernter
Qingqin Li, Nathan E Wineinger, Dong-Jing Fu, Ondrej Libiger, Larry Alphs, Adam Savitz, Srihari Gopal, Nadine Cohen, Nicholas J Schork