rs1801131

rs1801131 is a genetic variant on gene MTHFR associated with Gastrointestinal stromal tumor and Homocystinuria due to methylene tetrahydrofolate reductase deficiency.

This variant is located on chromosome 1. The variations at position 11794419 are the genetic letters A/A, C/C, G/G, T/T, A/C, C/G, G/T, A/T, A/G, C/T

Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs1801131 there are 10 currently known genotypes : A/A, C/C, G/G, T/T, A/C, C/G, G/T, A/T, A/G or C/T

The different genotypes of variant rs1801131 can affect the likelyhood of developing certain traits or conditions. Current research shows that 3 conditions and 0 traits are associated with rs1801131. The following table shows the relationship between genotypes and conditions and traits.

The genetic variant rs1801131 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs1801131. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.