Overview
rs1799931 is a genetic variant on gene NAT2.
This variant is located on chromosome 8. The variations at position 18400860 are the genetic letters A/A, G/G, A/G
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs1799931 there are 3 currently known genotypes : A/A, G/G or A/G
Short Overview
Variant Location
rs1799931 is located on gene NAT2 in chromsome 8. Use the genome browser to explore the location of rs1799931 and its genetic neighbourhood.
Conditions & Traits
rs1799931 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs1799931.
Pathogenicity
rs1799931 affects the following conditions:
There are currently 0 conditions associated with rs1799931.
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs on gene NAT2. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Conditions & Traits of rs1799931
Current research shows 0 conditions and 0 traits.
Conditions
0Pharmacogenetics
The genetic variant rs1799931 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs1799931. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Side Effects to DOCETAXEL.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to DOCETAXEL.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to DOCETAXEL.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to ISONIAZID.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to ISONIAZID.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Side Effects to ISONIAZID.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to PHENYTOIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to PHENYTOIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Side Effects to PHENYTOIN.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Side Effects to DOCETAXEL.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to DOCETAXEL.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to DOCETAXEL.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to ISONIAZID.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to ISONIAZID.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Side Effects to ISONIAZID.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to PHENYTOIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to PHENYTOIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Side Effects to PHENYTOIN.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Drugs related to rs1799931
All drugs that are linked to rs1799931 are listed here.
Studies and Sources
All of the resources below examine variant rs1799931
Jintana Sirivarasai, Suwanee Chanprasertyothin, Pornpimol Kongtip, Susan Woskie
Yujing Cheng, Qi Li, Xin Yang, Heng Ding, Wanlu Chen, Run Dai, Chan Zhang
Narmeen Mallah, Maruxa Zapata-Cachafeiro, Carmelo Aguirre, Eguzkiñe Ibarra-García, Itziar Palacios-Zabalza, Fernando Macías-García, María Piñeiro-Lamas, Luisa Ibáñez, Xavier Vidal, Lourdes Vendrell, Luis Martin-Arias, María Sáinz-Gil, Verónica Velasco-González, Manuel Bacariza-Cortiñas, Angel Salgado, Ana Estany-Gestal, Adolfo Figueiras