Overview
rs12979860 is a genetic variant.
This variant is located on chromosome 19. The variations at position 39248147 are the genetic letters C/C, G/G, T/T, C/G, G/T, C/T
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs12979860 there are 6 currently known genotypes : C/C, G/G, T/T, C/G, G/T or C/T
Short Overview
Variant Location
rs12979860 is located on gene in chromsome 19. Use the genome browser to explore the location of rs12979860 and its genetic neighbourhood.
Conditions & Traits
rs12979860 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs12979860.
Pathogenicity
rs12979860 affects the following conditions:
There are currently 0 conditions associated with rs12979860.
Pharmacogenetics
rs12979860 affects the following drugs:
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Conditions & Traits of rs12979860
Current research shows 0 conditions and 0 traits.
Conditions
0Pharmacogenetics
The genetic variant rs12979860 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs12979860. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Drug Effect to BOCEPREVIR.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have decreased Drug Effect to BOCEPREVIR.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have decreased Drug Effect to BOCEPREVIR.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Drug Effect to LEDIPASVIR.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have decreased Drug Effect to LEDIPASVIR.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have decreased Drug Effect to LEDIPASVIR.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Drug Effect to RIBAVIRIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have increased Drug Effect to RIBAVIRIN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Drug Effect to RIBAVIRIN.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Drug Effect to BOCEPREVIR.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have decreased Drug Effect to BOCEPREVIR.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have decreased Drug Effect to BOCEPREVIR.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Drug Effect to LEDIPASVIR.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have decreased Drug Effect to LEDIPASVIR.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have decreased Drug Effect to LEDIPASVIR.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Drug Effect to RIBAVIRIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have increased Drug Effect to RIBAVIRIN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Drug Effect to RIBAVIRIN.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Drugs related to rs12979860
All drugs that are linked to rs12979860 are listed here.
Studies and Sources
All of the resources below examine variant rs12979860
Leila Hajizadeh, Nader Mansour Samaei, Afsaneh Bazgir, Mehdi Agha Gholizadeh, Ayoob Khosravi
Xiaopeng Zhu, Mingfeng Xia, Xin Gao
Sock Hoai Chan, Yasmin Bylstra, Jing Xian Teo, Jyn Ling Kuan, Nicolas Bertin, Mar Gonzalez-Porta, Maxime Hebrard, Roberto Tirado-Magallanes, Joanna Hui Juan Tan, Justin Jeyakani, Zhihui Li, Jin Fang Chai, Yap Seng Chong, Sonia Davila, Liuh Ling Goh, Eng Sing Lee, Eleanor Wong, Tien Yin Wong, Tin Aung, Tin Aung, Kenneth Hon Kim Ban, Claire Bellis, Miao Li Chee, Miao Ling Chee, Wen Jie Chew, Calvin Woon-Loong Chin, Stuart A. Cook, Rinkoo Dalan, Rajkumar Dorajoo, Chester L. Drum, Paul Elliott, Johan G. Eriksson, Roger Foo, Daphne Gardner, Peter D. Gluckman, Denise Li Meng Goh, Kanika Jain, Sylvia Kam, Irfahan Kassam, Lakshmi Narayanan Lakshmanan, Caroline G. Lee, Jimmy Lee, Soo-Chin Lee, Yung Seng Lee, Hengtong Li, Chia Wei Lim, Tock Han Lim, Marie Loh, Sebastian Maurer-Stroh, Theresia Handayani Mina, Shi Qi Mok, Hong Kiat Ng, Chee Jian Pua, Elio Riboli, Tyler Hyungtaek Rim, Charumathi Sabanayagam, Wey Cheng Sim, Tavintharan Subramaniam, Ee Shien Tan, Eng King Tan, Erwin Tantoso, Darwin Tay, Yik Ying Teo, Yih Chung Tham, Li-xian Grace Toh, Pi Kuang Tsai, Rob M. van Dam, Lavanya Veeravalli, Gervais Wansaicheong Khin-lin, Andreas Wilm, Chengxi Yang, Fabian Yap, Yik Weng Yew, Shyam Prabhakar, Jianjun Liu, Ching-Yu Cheng, Birgit Eisenhaber, Neerja Karnani, Khai Pang Leong, Xueling Sim, Khung Keong Yeo, John C. Chambers, E-Shyong Tai, Patrick Tan, Saumya S. Jamuar, Joanne Ngeow, Weng Khong Lim