Overview
rs1057910 is a genetic variant on gene CYP2C9.
This variant is located on chromosome 10. The variations at position 94981296 are the genetic letters A/A, A/C
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs1057910 there are 2 currently known genotypes : A/A or A/C
Short Overview
Variant Location
rs1057910 is located on gene CYP2C9 in chromsome 10. Use the genome browser to explore the location of rs1057910 and its genetic neighbourhood.
Conditions & Traits
rs1057910 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs1057910.
Pathogenicity
rs1057910 affects the following conditions:
There are currently 0 conditions associated with rs1057910.
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs on gene CYP2C9. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
Did you know genetic variants affect drugs?
Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Conditions & Traits of rs1057910
Current research shows 0 conditions and 0 traits.
Conditions
0Pharmacogenetics
The genetic variant rs1057910 impacts how certain medications work in the body. This difference may cause some of us to require different dosage amounts to achieve the desired effects, while others might experience more apparent side-effects. As a result, healthcare providers may need to adjust prescriptions for those individuals with rs1057910. Ultimately, understanding our genetic makeup helps improve the overall effectiveness and usability of medications. Tailoring treatments based on genetics ensures a safer, more personalized healthcare experience.
Genotype
Level of evidence
Impacts
Summary
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Breakdown to IRBESARTAN.
more info
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/C have decreased Breakdown to IRBESARTAN.
more info
Legend:
Increased
Decreased
No known effect
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Breakdown to IRBESARTAN.
Level of evidence
More info
Genotype
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/C have decreased Breakdown to IRBESARTAN.
Level of evidence
More info
Legend:
Increased
Decreased
No known effect
Drugs related to rs1057910
All drugs that are linked to rs1057910 are listed here.
Studies and Sources
All of the resources below examine variant rs1057910
Yitian Zhou, Volker M. Lauschke
Ting-Liang Wang, Hong-Lei Li, Wen-Ye Tjong, Qian-Su Chen, Guan-Sheng Wu, Hai-Tao Zhu, Zi-Shan Hou, Shu Xu, Sheng-Jun Ma, Madeline Wu, Susan Tai
Fumihiko Takeuchi, Ralph McGinnis, Stephane Bourgeois, Chris Barnes, Niclas Eriksson, Nicole Soranzo, Pamela Whittaker, Venkatesh Ranganath, Vasudev Kumanduri, William McLaren, Lennart Holm, Jonatan Lindh, Anders Rane, Mia Wadelius, Panos Deloukas