Genes
RYR1
This gene is related to these conditions:
Effect of Variations on the RYR1
Variants are common variations in genes that can significantly impact the health and traits of an individual. This section shows all variants that are located on RYR1, as well as their associated conditions, traits and drugs.
Did you know that gene anomalies are relatively common?
On average, each person has approximately 100 to 400 genes with variations or mutations (with different genes being affected in different individuals). However, in most cases, the matching gene on the other chromosome in the pair is normal, which helps prevent potential negative effects. In the general population, the likelihood of an individual inheriting two copies of the same abnormal gene—and thus developing a genetic disorder—is very low. However, this risk increases significantly for children of parents who are closely related by blood.
Dr. Wallerstorfer
Conditions caused and influenced by RYR1
Genetic abnormalities can affect the chance of developing a condition by raising or lowering the risk. They can change how a gene works, leading to faulty or missing proteins. However, even with a higher genetic risk, a condition may not develop because factors like environment and lifestyle also have an impact.
Variants located on RYR1
The genetic code of a gene is virtually identical between differen people. Only a few individual letters differ from one person to the next.
Did you know genetic variations may affect drugs?
Genetic differences can affect how our body reacts to drugs. Some genes can make a drug work better or worse, and others can change how safe it is or how much of it you need.
Dr. Wallerstorfer
Pharmacogenetics
Genetic differences can affect how our bodies respond to medications. Some people’s genes can make a drug work better or worse, change how safe it is, or influence how much of the drug they need. These genetic changes can affect how the body processes medicine, like how quickly it is broken down or how it interacts with cells. For example, a genetic difference might cause a person’s body to break down a drug too fast, making it less effective, or too slowly, increasing the risk of side effects. This is why people can have different reactions to the same medication.
rs1801086
Drug
Genotype
Level of evidence
Impacts
Summary
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to DESFLURANE.
more info
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to DESFLURANE.
more info
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Side Effects to DESFLURANE.
more info
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/G have increased Side Effects to DESFLURANE.
more info
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to ENFLURANE.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to ENFLURANE.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Side Effects to ENFLURANE.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/G have increased Side Effects to ENFLURANE.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to HALOTHANE.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to HALOTHANE.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Side Effects to HALOTHANE.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/G have increased Side Effects to HALOTHANE.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to ISOFLURANE.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to ISOFLURANE.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Side Effects to ISOFLURANE.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/G have increased Side Effects to ISOFLURANE.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to SEVOFLURANE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to SEVOFLURANE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Side Effects to SEVOFLURANE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/G have increased Side Effects to SEVOFLURANE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
Legend:
Increased
Decreased
No known effect
rs28933396
Drug
Genotype
Level of evidence
Impacts
Summary
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to DESFLURANE.
more info
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to DESFLURANE.
more info
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to ENFLURANE.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to ENFLURANE.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to HALOTHANE.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to HALOTHANE.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to ISOFLURANE.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to ISOFLURANE.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to SEVOFLURANE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to SEVOFLURANE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
Legend:
Increased
Decreased
No known effect
rs28933397
Drug
Genotype
Level of evidence
Impacts
Summary
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have increased Side Effects to DESFLURANE.
more info
DESFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Side Effects to DESFLURANE.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have increased Side Effects to ENFLURANE.
more info
ENFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Side Effects to ENFLURANE.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have increased Side Effects to HALOTHANE.
more info
HALOTHANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Side Effects to HALOTHANE.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have increased Side Effects to ISOFLURANE.
more info
ISOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Side Effects to ISOFLURANE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/T have increased Side Effects to SEVOFLURANE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have increased Side Effects to SEVOFLURANE.
more info
Legend:
Increased
Decreased
No known effect
rs1801086
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to DESFLURANE.
More info
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to DESFLURANE.
More info
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Side Effects to DESFLURANE.
More info
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/G have increased Side Effects to DESFLURANE.
More info
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to ENFLURANE.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to ENFLURANE.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Side Effects to ENFLURANE.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/G have increased Side Effects to ENFLURANE.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to HALOTHANE.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to HALOTHANE.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Side Effects to HALOTHANE.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/G have increased Side Effects to HALOTHANE.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to ISOFLURANE.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to ISOFLURANE.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Side Effects to ISOFLURANE.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/G have increased Side Effects to ISOFLURANE.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to SEVOFLURANE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to SEVOFLURANE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Side Effects to SEVOFLURANE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/G have increased Side Effects to SEVOFLURANE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Legend:
Increased
Decreased
No known effect
rs28933396
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to DESFLURANE.
More info
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to DESFLURANE.
More info
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to ENFLURANE.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to ENFLURANE.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to HALOTHANE.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to HALOTHANE.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to ISOFLURANE.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to ISOFLURANE.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to SEVOFLURANE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to SEVOFLURANE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Legend:
Increased
Decreased
No known effect
rs28933397
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have increased Side Effects to DESFLURANE.
More info
Drug
DESFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Side Effects to DESFLURANE.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have increased Side Effects to ENFLURANE.
More info
Drug
ENFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Side Effects to ENFLURANE.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have increased Side Effects to HALOTHANE.
More info
Drug
HALOTHANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Side Effects to HALOTHANE.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have increased Side Effects to ISOFLURANE.
More info
Drug
ISOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Side Effects to ISOFLURANE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/T have increased Side Effects to SEVOFLURANE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have increased Side Effects to SEVOFLURANE.
More info
Legend:
Increased
Decreased
No known effect