Effect of Variations on the ABCB1
Variants are common variations in genes that can significantly impact the health and traits of an individual. This section shows all variants that are located on ABCB1, as well as their associated conditions, traits and drugs.
Did you know that gene anomalies are relatively common?
On average, each person has approximately 100 to 400 genes with variations or mutations (with different genes being affected in different individuals). However, in most cases, the matching gene on the other chromosome in the pair is normal, which helps prevent potential negative effects. In the general population, the likelihood of an individual inheriting two copies of the same abnormal gene—and thus developing a genetic disorder—is very low. However, this risk increases significantly for children of parents who are closely related by blood.
Dr. Wallerstorfer
Conditions caused and influenced by ABCB1
Genetic abnormalities can affect the chance of developing a condition by raising or lowering the risk. They can change how a gene works, leading to faulty or missing proteins. However, even with a higher genetic risk, a condition may not develop because factors like environment and lifestyle also have an impact.
Variants located on ABCB1
The genetic code of a gene is virtually identical between differen people. Only a few individual letters differ from one person to the next.
Did you know genetic variations may affect drugs?
Genetic differences can affect how our body reacts to drugs. Some genes can make a drug work better or worse, and others can change how safe it is or how much of it you need.
Dr. Wallerstorfer
Pharmacogenetics
Genetic differences can affect how our bodies respond to medications. Some people’s genes can make a drug work better or worse, change how safe it is, or influence how much of the drug they need. These genetic changes can affect how the body processes medicine, like how quickly it is broken down or how it interacts with cells. For example, a genetic difference might cause a person’s body to break down a drug too fast, making it less effective, or too slowly, increasing the risk of side effects. This is why people can have different reactions to the same medication.
rs3842
Drug
Genotype
Level of evidence
Impacts
Summary
EFAVIRENZ
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
EFAVIRENZ
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
EFAVIRENZ
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype T/T have decreased Breakdown to EFAVIRENZ.
more info
OLANZAPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype C/C have increased Side Effects to OLANZAPINE.
more info
OLANZAPINE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
OLANZAPINE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
Legend:
Increased
Decreased
No known effect
rs1045642
Drug
Genotype
Level of evidence
Impacts
Summary
ANASTROZOLE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
ANASTROZOLE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
ANASTROZOLE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
CAPECITABINE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
CAPECITABINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to CAPECITABINE.
more info
CAPECITABINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to CAPECITABINE.
more info
CARBAMAZEPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect and decreased Dosage to CARBAMAZEPINE.
more info
CARBAMAZEPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Drug Effect and increased Dosage to CARBAMAZEPINE.
more info
CARBAMAZEPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Dosage to CARBAMAZEPINE.
more info
CISPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect and increased Side Effects to CISPLATIN.
more info
CISPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to CISPLATIN.
more info
CISPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect and increased Side Effects to CISPLATIN.
more info
CYCLOPHOSPHAMIDE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
CYCLOPHOSPHAMIDE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
CYCLOPHOSPHAMIDE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to CYCLOPHOSPHAMIDE.
more info
CYCLOSPORINE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
CYCLOSPORINE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
CYCLOSPORINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to CYCLOSPORINE.
more info
CYTARABINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to CYTARABINE.
more info
CYTARABINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to CYTARABINE.
more info
CYTARABINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to CYTARABINE.
more info
DEXAMETHASONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to DEXAMETHASONE.
more info
DEXAMETHASONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to DEXAMETHASONE.
more info
DEXAMETHASONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to DEXAMETHASONE.
more info
DOCETAXEL
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
DOCETAXEL
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
DOCETAXEL
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
EFAVIRENZ
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect, increased Breakdown and increased Side Effects to EFAVIRENZ.
more info
EFAVIRENZ
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Drug Effect and increased Breakdown to EFAVIRENZ.
more info
EFAVIRENZ
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect, decreased Breakdown and increased Side Effects to EFAVIRENZ.
more info
ETOPOSIDE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Breakdown and increased Side Effects to ETOPOSIDE.
more info
ETOPOSIDE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Breakdown to ETOPOSIDE.
more info
ETOPOSIDE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Breakdown to ETOPOSIDE.
more info
EVEROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to EVEROLIMUS.
more info
EVEROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to EVEROLIMUS.
more info
EVEROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
FENTANYL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect, decreased Dosage and increased Side Effects to FENTANYL.
more info
FENTANYL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect and decreased Dosage to FENTANYL.
more info
FENTANYL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Drug Effect and increased Dosage to FENTANYL.
more info
FLUOROURACIL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect and increased Side Effects to FLUOROURACIL.
more info
FLUOROURACIL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect and increased Side Effects to FLUOROURACIL.
more info
FLUOROURACIL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect and increased Side Effects to FLUOROURACIL.
more info
GRANISETRON
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to GRANISETRON.
more info
GRANISETRON
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Drug Effect to GRANISETRON.
more info
GRANISETRON
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to GRANISETRON.
more info
ISONIAZID
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to ISONIAZID.
more info
ISONIAZID
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to ISONIAZID.
more info
ISONIAZID
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Side Effects to ISONIAZID.
more info
LANSOPRAZOLE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Breakdown to LANSOPRAZOLE.
more info
LANSOPRAZOLE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Breakdown to LANSOPRAZOLE.
more info
LANSOPRAZOLE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Breakdown to LANSOPRAZOLE.
more info
METHOTREXATE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to METHOTREXATE.
more info
METHOTREXATE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to METHOTREXATE.
more info
METHOTREXATE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to METHOTREXATE.
more info
METHYLPREDNISOLONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
METHYLPREDNISOLONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to METHYLPREDNISOLONE.
more info
METHYLPREDNISOLONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to METHYLPREDNISOLONE.
more info
MODAFINIL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect to MODAFINIL.
more info
MODAFINIL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to MODAFINIL.
more info
MODAFINIL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to MODAFINIL.
more info
NEVIRAPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Side Effects to NEVIRAPINE.
more info
NEVIRAPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Side Effects to NEVIRAPINE.
more info
NEVIRAPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to NEVIRAPINE.
more info
OLANZAPINE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
OLANZAPINE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
OLANZAPINE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
OMEPRAZOLE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to OMEPRAZOLE.
more info
OMEPRAZOLE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Drug Effect to OMEPRAZOLE.
more info
OMEPRAZOLE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to OMEPRAZOLE.
more info
ONDANSETRON
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
ONDANSETRON
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to ONDANSETRON.
more info
ONDANSETRON
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to ONDANSETRON.
more info
OXALIPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect to OXALIPLATIN.
more info
OXALIPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to OXALIPLATIN.
more info
OXALIPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
OXCARBAZEPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect to OXCARBAZEPINE.
more info
OXCARBAZEPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Drug Effect to OXCARBAZEPINE.
more info
OXCARBAZEPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Drug Effect to OXCARBAZEPINE.
more info
OXYCODONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
OXYCODONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
OXYCODONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PACLITAXEL
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PACLITAXEL
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PACLITAXEL
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PHENYTOIN
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PHENYTOIN
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PHENYTOIN
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PREDNISOLONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PREDNISOLONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to PREDNISOLONE.
more info
PREDNISOLONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to PREDNISOLONE.
more info
PREDNISONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PREDNISONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PREDNISONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
RISPERIDONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
RISPERIDONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
RISPERIDONE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
RITONAVIR
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Dosage to RITONAVIR.
more info
RITONAVIR
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
RITONAVIR
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
SIMVASTATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to SIMVASTATIN.
more info
SIMVASTATIN
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
SIMVASTATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to SIMVASTATIN.
more info
SIROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
SIROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
SIROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
TACROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect, decreased Breakdown and decreased Dosage to TACROLIMUS.
more info
TACROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Drug Effect, increased Breakdown, decreased Dosage and increased Side Effects to TACROLIMUS.
more info
TACROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Drug Effect, increased Breakdown and increased Dosage to TACROLIMUS.
more info
Legend:
Increased
Decreased
No known effect
rs1128503
Drug
Genotype
Level of evidence
Impacts
Summary
CAPECITABINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Side Effects to CAPECITABINE.
more info
CAPECITABINE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
CAPECITABINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to CAPECITABINE.
more info
CARBAMAZEPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Breakdown to CARBAMAZEPINE.
more info
CARBAMAZEPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Breakdown to CARBAMAZEPINE.
more info
CARBAMAZEPINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Breakdown to CARBAMAZEPINE.
more info
CISPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to CISPLATIN.
more info
CISPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
CISPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to CISPLATIN.
more info
CYCLOPHOSPHAMIDE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to CYCLOPHOSPHAMIDE.
more info
CYCLOPHOSPHAMIDE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
CYCLOPHOSPHAMIDE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to CYCLOPHOSPHAMIDE.
more info
CYCLOSPORINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Breakdown and decreased Dosage to CYCLOSPORINE.
more info
CYCLOSPORINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Breakdown and increased Dosage to CYCLOSPORINE.
more info
CYCLOSPORINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Breakdown and increased Dosage to CYCLOSPORINE.
more info
CYTARABINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to CYTARABINE.
more info
CYTARABINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to CYTARABINE.
more info
CYTARABINE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to CYTARABINE.
more info
EFAVIRENZ
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
EFAVIRENZ
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
EFAVIRENZ
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
FENTANYL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect, increased Dosage and increased Side Effects to FENTANYL.
more info
FENTANYL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect and decreased Dosage to FENTANYL.
more info
FENTANYL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Drug Effect and decreased Dosage to FENTANYL.
more info
GEFITINIB
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to GEFITINIB.
more info
GEFITINIB
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Side Effects to GEFITINIB.
more info
GEFITINIB
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Side Effects to GEFITINIB.
more info
METHOTREXATE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect and increased Side Effects to METHOTREXATE.
more info
METHOTREXATE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Side Effects to METHOTREXATE.
more info
METHOTREXATE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Side Effects to METHOTREXATE.
more info
MODAFINIL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect to MODAFINIL.
more info
MODAFINIL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to MODAFINIL.
more info
MODAFINIL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to MODAFINIL.
more info
OXALIPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to OXALIPLATIN.
more info
OXALIPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to OXALIPLATIN.
more info
OXALIPLATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to OXALIPLATIN.
more info
PACLITAXEL
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Side Effects to PACLITAXEL.
more info
PACLITAXEL
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
PACLITAXEL
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
RISPERIDONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to RISPERIDONE.
more info
RISPERIDONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to RISPERIDONE.
more info
RISPERIDONE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect to RISPERIDONE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have decreased Drug Effect and increased Side Effects to SEVOFLURANE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have decreased Drug Effect and increased Side Effects to SEVOFLURANE.
more info
SEVOFLURANE
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Drug Effect to SEVOFLURANE.
more info
SIMVASTATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to SIMVASTATIN.
more info
SIMVASTATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to SIMVASTATIN.
more info
SIMVASTATIN
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have decreased Drug Effect and increased Side Effects to SIMVASTATIN.
more info
SIROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Dosage to SIROLIMUS.
more info
SIROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Dosage to SIROLIMUS.
more info
SIROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
TACROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Drug Effect to TACROLIMUS.
more info
TACROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Drug Effect to TACROLIMUS.
more info
TACROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype G/G have increased Drug Effect to TACROLIMUS.
more info
TEMOZOLOMIDE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
TEMOZOLOMIDE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
TEMOZOLOMIDE
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
TEMSIROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/A have increased Dosage to TEMSIROLIMUS.
more info
TEMSIROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
Individuals with the genotype A/G have increased Dosage to TEMSIROLIMUS.
more info
TEMSIROLIMUS
Breakdown
Drug Effect
Side Effects
Dosage
No summary available.
more info
Legend:
Increased
Decreased
No known effect
rs3842
Drug
EFAVIRENZ
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
EFAVIRENZ
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
EFAVIRENZ
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype T/T have decreased Breakdown to EFAVIRENZ.
More info
Drug
OLANZAPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype C/C have increased Side Effects to OLANZAPINE.
More info
Drug
OLANZAPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
OLANZAPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Legend:
Increased
Decreased
No known effect
rs1045642
Drug
ANASTROZOLE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
ANASTROZOLE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
ANASTROZOLE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
CAPECITABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
CAPECITABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to CAPECITABINE.
More info
Drug
CAPECITABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to CAPECITABINE.
More info
Drug
CARBAMAZEPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Drug Effect and decreased Dosage to CARBAMAZEPINE.
More info
Drug
CARBAMAZEPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Drug Effect and increased Dosage to CARBAMAZEPINE.
More info
Drug
CARBAMAZEPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Dosage to CARBAMAZEPINE.
More info
Drug
CISPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect and increased Side Effects to CISPLATIN.
More info
Drug
CISPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to CISPLATIN.
More info
Drug
CISPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect and increased Side Effects to CISPLATIN.
More info
Drug
CYCLOPHOSPHAMIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
CYCLOPHOSPHAMIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
CYCLOPHOSPHAMIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to CYCLOPHOSPHAMIDE.
More info
Drug
CYCLOSPORINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
CYCLOSPORINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
CYCLOSPORINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to CYCLOSPORINE.
More info
Drug
CYTARABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to CYTARABINE.
More info
Drug
CYTARABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to CYTARABINE.
More info
Drug
CYTARABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to CYTARABINE.
More info
Drug
DEXAMETHASONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to DEXAMETHASONE.
More info
Drug
DEXAMETHASONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to DEXAMETHASONE.
More info
Drug
DEXAMETHASONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to DEXAMETHASONE.
More info
Drug
DOCETAXEL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
DOCETAXEL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
DOCETAXEL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
EFAVIRENZ
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect, increased Breakdown and increased Side Effects to EFAVIRENZ.
More info
Drug
EFAVIRENZ
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Drug Effect and increased Breakdown to EFAVIRENZ.
More info
Drug
EFAVIRENZ
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect, decreased Breakdown and increased Side Effects to EFAVIRENZ.
More info
Drug
ETOPOSIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Breakdown and increased Side Effects to ETOPOSIDE.
More info
Drug
ETOPOSIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Breakdown to ETOPOSIDE.
More info
Drug
ETOPOSIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Breakdown to ETOPOSIDE.
More info
Drug
EVEROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to EVEROLIMUS.
More info
Drug
EVEROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to EVEROLIMUS.
More info
Drug
EVEROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
FENTANYL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Drug Effect, decreased Dosage and increased Side Effects to FENTANYL.
More info
Drug
FENTANYL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect and decreased Dosage to FENTANYL.
More info
Drug
FENTANYL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Drug Effect and increased Dosage to FENTANYL.
More info
Drug
FLUOROURACIL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect and increased Side Effects to FLUOROURACIL.
More info
Drug
FLUOROURACIL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect and increased Side Effects to FLUOROURACIL.
More info
Drug
FLUOROURACIL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect and increased Side Effects to FLUOROURACIL.
More info
Drug
GRANISETRON
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to GRANISETRON.
More info
Drug
GRANISETRON
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Drug Effect to GRANISETRON.
More info
Drug
GRANISETRON
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to GRANISETRON.
More info
Drug
ISONIAZID
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to ISONIAZID.
More info
Drug
ISONIAZID
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to ISONIAZID.
More info
Drug
ISONIAZID
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Side Effects to ISONIAZID.
More info
Drug
LANSOPRAZOLE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Breakdown to LANSOPRAZOLE.
More info
Drug
LANSOPRAZOLE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Breakdown to LANSOPRAZOLE.
More info
Drug
LANSOPRAZOLE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Breakdown to LANSOPRAZOLE.
More info
Drug
METHOTREXATE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to METHOTREXATE.
More info
Drug
METHOTREXATE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to METHOTREXATE.
More info
Drug
METHOTREXATE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to METHOTREXATE.
More info
Drug
METHYLPREDNISOLONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
METHYLPREDNISOLONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to METHYLPREDNISOLONE.
More info
Drug
METHYLPREDNISOLONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to METHYLPREDNISOLONE.
More info
Drug
MODAFINIL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Drug Effect to MODAFINIL.
More info
Drug
MODAFINIL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to MODAFINIL.
More info
Drug
MODAFINIL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to MODAFINIL.
More info
Drug
NEVIRAPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Side Effects to NEVIRAPINE.
More info
Drug
NEVIRAPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Side Effects to NEVIRAPINE.
More info
Drug
NEVIRAPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to NEVIRAPINE.
More info
Drug
OLANZAPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
OLANZAPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
OLANZAPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
OMEPRAZOLE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to OMEPRAZOLE.
More info
Drug
OMEPRAZOLE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Drug Effect to OMEPRAZOLE.
More info
Drug
OMEPRAZOLE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to OMEPRAZOLE.
More info
Drug
ONDANSETRON
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
ONDANSETRON
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to ONDANSETRON.
More info
Drug
ONDANSETRON
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to ONDANSETRON.
More info
Drug
OXALIPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Drug Effect to OXALIPLATIN.
More info
Drug
OXALIPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to OXALIPLATIN.
More info
Drug
OXALIPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
OXCARBAZEPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Drug Effect to OXCARBAZEPINE.
More info
Drug
OXCARBAZEPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Drug Effect to OXCARBAZEPINE.
More info
Drug
OXCARBAZEPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Drug Effect to OXCARBAZEPINE.
More info
Drug
OXYCODONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
OXYCODONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
OXYCODONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PACLITAXEL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PACLITAXEL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PACLITAXEL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PHENYTOIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PHENYTOIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PHENYTOIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PREDNISOLONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PREDNISOLONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to PREDNISOLONE.
More info
Drug
PREDNISOLONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to PREDNISOLONE.
More info
Drug
PREDNISONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PREDNISONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PREDNISONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
RISPERIDONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
RISPERIDONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
RISPERIDONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
RITONAVIR
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Dosage to RITONAVIR.
More info
Drug
RITONAVIR
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
RITONAVIR
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
SIMVASTATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to SIMVASTATIN.
More info
Drug
SIMVASTATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
SIMVASTATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to SIMVASTATIN.
More info
Drug
SIROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
SIROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
SIROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
TACROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect, decreased Breakdown and decreased Dosage to TACROLIMUS.
More info
Drug
TACROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Drug Effect, increased Breakdown, decreased Dosage and increased Side Effects to TACROLIMUS.
More info
Drug
TACROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Drug Effect, increased Breakdown and increased Dosage to TACROLIMUS.
More info
Legend:
Increased
Decreased
No known effect
rs1128503
Drug
CAPECITABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Side Effects to CAPECITABINE.
More info
Drug
CAPECITABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
CAPECITABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to CAPECITABINE.
More info
Drug
CARBAMAZEPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Breakdown to CARBAMAZEPINE.
More info
Drug
CARBAMAZEPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Breakdown to CARBAMAZEPINE.
More info
Drug
CARBAMAZEPINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Breakdown to CARBAMAZEPINE.
More info
Drug
CISPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to CISPLATIN.
More info
Drug
CISPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
CISPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to CISPLATIN.
More info
Drug
CYCLOPHOSPHAMIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to CYCLOPHOSPHAMIDE.
More info
Drug
CYCLOPHOSPHAMIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
CYCLOPHOSPHAMIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to CYCLOPHOSPHAMIDE.
More info
Drug
CYCLOSPORINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Breakdown and decreased Dosage to CYCLOSPORINE.
More info
Drug
CYCLOSPORINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Breakdown and increased Dosage to CYCLOSPORINE.
More info
Drug
CYCLOSPORINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Breakdown and increased Dosage to CYCLOSPORINE.
More info
Drug
CYTARABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to CYTARABINE.
More info
Drug
CYTARABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to CYTARABINE.
More info
Drug
CYTARABINE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to CYTARABINE.
More info
Drug
EFAVIRENZ
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
EFAVIRENZ
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
EFAVIRENZ
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
FENTANYL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Drug Effect, increased Dosage and increased Side Effects to FENTANYL.
More info
Drug
FENTANYL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect and decreased Dosage to FENTANYL.
More info
Drug
FENTANYL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Drug Effect and decreased Dosage to FENTANYL.
More info
Drug
GEFITINIB
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to GEFITINIB.
More info
Drug
GEFITINIB
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Side Effects to GEFITINIB.
More info
Drug
GEFITINIB
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Side Effects to GEFITINIB.
More info
Drug
METHOTREXATE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect and increased Side Effects to METHOTREXATE.
More info
Drug
METHOTREXATE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Side Effects to METHOTREXATE.
More info
Drug
METHOTREXATE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Side Effects to METHOTREXATE.
More info
Drug
MODAFINIL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Drug Effect to MODAFINIL.
More info
Drug
MODAFINIL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to MODAFINIL.
More info
Drug
MODAFINIL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to MODAFINIL.
More info
Drug
OXALIPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to OXALIPLATIN.
More info
Drug
OXALIPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to OXALIPLATIN.
More info
Drug
OXALIPLATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to OXALIPLATIN.
More info
Drug
PACLITAXEL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Side Effects to PACLITAXEL.
More info
Drug
PACLITAXEL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
PACLITAXEL
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
RISPERIDONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to RISPERIDONE.
More info
Drug
RISPERIDONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to RISPERIDONE.
More info
Drug
RISPERIDONE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect to RISPERIDONE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have decreased Drug Effect and increased Side Effects to SEVOFLURANE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have decreased Drug Effect and increased Side Effects to SEVOFLURANE.
More info
Drug
SEVOFLURANE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Drug Effect to SEVOFLURANE.
More info
Drug
SIMVASTATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to SIMVASTATIN.
More info
Drug
SIMVASTATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to SIMVASTATIN.
More info
Drug
SIMVASTATIN
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have decreased Drug Effect and increased Side Effects to SIMVASTATIN.
More info
Drug
SIROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Dosage to SIROLIMUS.
More info
Drug
SIROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Dosage to SIROLIMUS.
More info
Drug
SIROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
TACROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Drug Effect to TACROLIMUS.
More info
Drug
TACROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Drug Effect to TACROLIMUS.
More info
Drug
TACROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype G/G have increased Drug Effect to TACROLIMUS.
More info
Drug
TEMOZOLOMIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
TEMOZOLOMIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
TEMOZOLOMIDE
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Drug
TEMSIROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/A have increased Dosage to TEMSIROLIMUS.
More info
Drug
TEMSIROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
Individuals with the genotype A/G have increased Dosage to TEMSIROLIMUS.
More info
Drug
TEMSIROLIMUS
Genotype
Level of evidence
Impacts
Breakdown
Drug Effect
Side Effects
Dosage
Summary
No summary available.
More info
Legend:
Increased
Decreased
No known effect