Perineurioma is a rare and usually benign tumor that grows from the covering of a nerve. It often grows slowly over months or years and is most often recognized in teenagers and young adults, though it can occur at other ages. Many people with perineurioma notice a painless lump, weakness, numbness, or tingling, and the early symptoms of perineurioma can depend on which nerve is affected. Not everyone will have the same experience. Perineurioma is not usually life-threatening, and treatment often involves monitoring or surgery if it is causing symptoms or getting larger.
How many people live with Perineurioma?
Perineurioma appears to be very rare, but there is no widely accepted recent estimate for how many people are living with it worldwide or in the United States. Most published information comes from individual case reports and small case series, so reliable population counts are not consistently available.
Overview
PerineuriomaSymptoms
Perineurioma often causes a slow-growing, painless lump or weakness, numbness, or tingling if it affects a nerve. Early symptoms of perineurioma can be subtle, and some people notice clumsiness or muscle thinning in one area.
Outlook and prognosis
Perineurioma is usually slow-growing and noncancerous, so the outlook is often very good. After treatment, many people do well long term, though follow-up may be needed if the tumor is hard to remove fully or presses on a nerve.
Causes and risk factors
Perineurioma usually has no clear cause. Most cases seem to arise sporadically, sometimes with changes in tumor cell genes such as chromosome 22; no proven lifestyle or environmental risk factors are known, and it is rarely inherited.
Genetic influences
Genetics can matter in perineurioma, but it is usually linked to changes that arise in the affected tissue rather than changes inherited from a parent. Many people with perineurioma do not have a family history, and inherited risk is not usually a major factor.
Diagnosis
Perineurioma is diagnosed by combining symptoms, imaging such as MRI, and a tissue sample under the microscope. Doctors usually confirm the diagnosis of perineurioma with special lab staining to tell it apart from other nerve tumors.
Treatment and drugs
Perineurioma is often treated with monitoring or surgery if a nerve tumor is growing, painful, or weakening movement. When removal is possible, surgeons try to protect the nerve. Physical therapy can help with strength and function afterward.
Symptoms
Perineurioma often grows slowly, so changes can be easy to miss at first. In daily routines, this might show up as small but noticeable changes. Many people with perineurioma notice either a painless lump or gradual nerve problems such as weakness, numbness, or tingling, depending on where it grows. The early symptoms of perineurioma can be subtle and may build over months or years.
Some people with perineurioma notice a small lump under the skin or in deeper soft tissue. It often grows slowly and may not hurt, which is one reason it can go unnoticed for a while.
When perineurioma involves a nerve, it can cause numbness, pins-and-needles, or a reduced sense of touch. This may be most noticeable in one hand, foot, arm, or leg rather than all over the body.
Weakness is a common symptom in intraneural perineurioma, meaning the tumor is growing within a nerve. Everyday tasks like lifting the front of the foot, gripping objects, or climbing stairs can start to feel harder on one side.
Over time, the affected muscles may become smaller because they are not getting normal nerve signals. This can show up as thinning in part of the hand, arm, lower leg, or foot.
How people usually first notice Perineurioma?
People usually first notice perineurioma when a small, slow-growing lump appears under the skin or when a nerve-related problem seems to creep in without a clear reason. If the tumor is near or within a nerve, early signs can include numbness, tingling, weakness, or a gradual loss of muscle control in one area, while some people have no symptoms at all and learn about it after imaging or surgery for what seemed like another lump. Because perineurioma is typically benign and often grows slowly, these first warning signs can be easy to miss, but a new persistent lump or unexplained nerve symptoms are good reasons to get checked.
Types of Perineurioma
Perineurioma can affect daily life in different ways depending on where the growth develops. This rare, usually noncancerous nerve-related tumor is most often grouped into intraneural and soft tissue forms, and some experts also recognize a small skin-based form called sclerosing perineurioma. Symptoms don’t always look the same for everyone. For many living with perineurioma, the main difference between the types of perineurioma is whether they mainly cause weakness from nerve involvement or show up as a slow-growing lump.
Intraneural
This type grows within a nerve, so it often causes weakness, muscle shrinking, numbness, or tingling in the area served by that nerve. Someone might first notice a hand that grips less firmly or a foot that starts to drag rather than a visible lump. Symptoms often build slowly over time and may be more noticeable than pain.
Soft tissue
This type grows in the soft tissues outside a nerve and often appears as a painless, slow-growing lump under the skin or deeper in an arm, leg, or trunk. Many people with this form have few symptoms unless the mass presses on nearby structures. When symptoms do happen, they are more often local discomfort or swelling than clear nerve-related weakness.
Sclerosing
This is a small, usually skin-based variant that most often appears on the fingers, hands, or palms as a firm bump. It tends to be more of a cosmetic or local nuisance than a cause of nerve problems. Having one type doesn’t necessarily mean you’ll develop the others.
Can I slow down the onset of symptoms?
Probably not in any proven way. For perineurioma, which is a rare growth in the tissue around a nerve, there is no good evidence that lifestyle changes like diet, exercise, sleep, or supplements can meaningfully delay when symptoms begin, although general good health may still help overall strength and well-being. There is also no established medicine to prevent it, so the most helpful step is getting checked early if weakness, numbness, pain, or a lump appears; that cannot guarantee a delay, but it can help people with perineurioma get the right monitoring and care sooner.
What genetics can tell you about symptoms
For people with perineurioma, genetics can confirm that this is a distinct nerve-sheath growth, and some tumors have changes involving chromosome 22 or other gene changes, but these findings do not yet reliably predict which symptoms will happen. In day-to-day life, symptoms are still understood mainly by where the growth is and whether it affects a nerve, so some may notice a painless lump while others have weakness, numbness, or tingling if a nerve is involved. At this point, genetic testing is more helpful for diagnosis and research than for telling when symptoms will start or how severe they will become.
Causes and risk factors
For many people, perineurioma appears without a clear cause. It likely starts when cells around a nerve pick up gene changes over time, and these changes are usually not inherited from a parent. Researchers are still learning how these pieces fit together. No strong lifestyle or environmental risk factors for perineurioma are known, and it is not clearly linked to things like diet, exercise, smoking, or a past injury. Age and the type of perineurioma may shape who gets it, but most people with a nerve lump or early symptoms of perineurioma did nothing to cause it.
What are the most common causes or risk factors?
For most people with perineurioma, the exact cause is not known, but it is usually linked to random gene changes that develop in the tumor cells during life rather than something inherited from a parent. There are no well-proven everyday risk factors such as diet, smoking, injury, or infection. Age may play a small role depending on the type, with some nerve-related perineuriomas seen more often in children, teens, and young adults, while others are more common in adults.
Environmental and biological risk factors
Perineurioma is a rare tumor, and clear environmental or biological risk factors have not been firmly confirmed. When people look up the causes of perineurioma, the honest answer is that most cases seem to happen sporadically, without an obvious trigger. Awareness of both biological and environmental influences helps you feel prepared, but with perineurioma the main message is that no common exposure or health condition has been shown to clearly cause it.
Intraneural perineurioma is seen more often in children, teens, and young adults, while soft tissue perineurioma is more often found in adults. This is an age pattern doctors have noticed, not a proven cause.
Perineurioma can affect people of any sex, and no strong, consistent sex-based risk pattern has been established. In other words, sex does not appear to be a major biological risk factor.
No environmental exposure has been clearly shown to raise the risk of perineurioma. At this point, there is no well-established outside trigger linked to most cases.
No common medical condition has been proven to strongly increase the chance of perineurioma. Most people diagnosed with perineurioma do not have a clear biological trigger that explains why it developed.
Genetic risk factors
Perineurioma is usually linked to gene changes that happen only in the tumor itself, not to a condition passed down through families. People often ask whether perineurioma is hereditary, and in most cases the answer is no. The exact genetic finding can differ by subtype, especially between tumors that grow within a nerve and those that form in soft tissue.
Not inherited: Most perineurioma cases are sporadic, meaning they happen without a clear family pattern. Parents do not usually pass this tumor risk directly to their children.
Tumor-only changes: The main genetic changes in perineurioma usually arise only in the tumor cells. Because the rest of the body does not carry these changes, they are not usually inherited.
Chromosome 22 loss: Some perineuriomas lose a small piece of chromosome 22, which contains genes that help control cell growth. This is one of the best-known genetic findings in perineurioma.
TRAF7 changes: Many intraneural perineuriomas have changes in a gene called TRAF7. This helps explain why some tumors develop inside a nerve rather than in nearby soft tissue.
Subtype differences: The genetic pattern can vary between intraneural perineurioma and soft tissue perineurioma. Because of this, one test result does not fit every case.
Lifestyle risk factors
There are no well-established lifestyle habits known to cause perineurioma. For most people, how lifestyle affects perineurioma is more about symptom burden, nerve irritation, recovery after treatment, and the chance of functional decline than about tumor formation itself. The most relevant factors are those that increase pressure on the affected nerve, slow healing, or make weakness and pain harder to manage.
Repeated motion, prolonged pressure, or overuse of the involved limb can aggravate pain, tingling, or weakness from a perineurioma. Reducing mechanical stress may help limit day-to-day symptom flare-ups and protect function.
Regular, tailored exercise can help preserve strength, joint mobility, and balance when a perineurioma affects movement or sensation. Very intense or poorly adapted activity may worsen symptoms if it repeatedly loads the affected nerve.
Excess body weight can increase mechanical stress on nerves and make mobility limitations more noticeable, especially when the tumor affects a leg or weight-bearing area. Keeping weight in a healthy range may improve comfort and physical function.
Tobacco use does not appear to be a proven cause of perineurioma, but it can impair blood flow, nerve health, and wound healing. This may matter more if surgery, biopsy recovery, or long-term nerve function is a concern.
Risk prevention
Perineurioma is a rare, usually benign nerve-related tumor, and there is no proven way to prevent the tumor itself because its exact cause is often unclear. For many people, prevention is really about lowering the chance of delays, nerve damage, or avoidable complications by getting new symptoms checked early. Prevention is about lowering risk, not eliminating it completely.
New numbness, tingling, weakness, or a slowly growing lump should be checked rather than watched for months. Catching possible early symptoms of perineurioma sooner can help protect nerve function and guide the right imaging or follow-up.
Repeated pressure on one area, long periods in awkward positions, and poorly fitting braces or gear can irritate nerves that are already vulnerable. While this does not prevent perineurioma, it may reduce added pain, weakness, or loss of function.
Protecting hands, feet, arms, and legs during work, sports, and daily tasks may help lower the risk of nerve injury around an affected area. Simple steps such as good footwear, padding, and safe lifting habits can matter.
If you have been diagnosed with perineurioma, keeping follow-up visits and scans when recommended helps track changes over time. Prevention works best when combined with regular check-ups.
Can you prevent Perineurioma?
No, there is no known way to prevent perineurioma. This rare, usually noncancerous growth tends to happen by chance, and there are no proven lifestyle changes, screenings, or medicines that are known to stop it from developing.
Transmission
Perineurioma is not infectious, so it cannot be spread from one person to another through touch, coughing, sex, blood, or everyday contact. Many living with Perineurioma find it reassuring to know that it is a benign nerve sheath growth, not a germ or virus.
If you are wondering how Perineurioma is inherited, it usually is not passed from parent to child. Most cases appear sporadically, meaning they develop in the affected tissue itself rather than being shared within a family.
When to test your genes
For perineurioma, routine inherited genetic testing is usually not needed because most cases are isolated and not linked to a known family-risk gene. Testing may be worth discussing if tumors are multiple, occur at a young age, the diagnosis is uncertain, or there is a family history of nerve-sheath tumors or related syndromes.
Diagnosis
Perineurioma is usually diagnosed after a slow-growing lump, nerve-related symptoms, or unexplained weakness leads to a medical visit. Some people notice a patch of numbness that does not go away, while others find that a hand, foot, or part of the face is gradually getting weaker. It’s natural to worry when symptoms don’t have a clear explanation. The diagnosis of perineurioma usually combines an exam, imaging, and a close look at tissue under the microscope.
Doctors ask when the lump or nerve symptoms began and whether they have changed over time. They also check for weakness, numbness, pain, or muscle wasting that could point to the affected nerve.
The exam looks for a palpable lump, changes in strength, altered sensation, and reduced reflexes. In many living with perineurioma, these findings help show which nerve or area may be involved.
MRI is often the main imaging test because it can show the size, location, and shape of the growth. It also helps doctors see whether the tumor seems to arise from a nerve and plan the safest next step.
If weakness or numbness is present, nerve conduction studies and electromyography may be used to check how well the nerve and muscles are working. These tests do not confirm perineurioma by themselves, but they can support the diagnosis and help rule out other causes.
How is Perineurioma diagnosed?
Doctors usually start with the symptoms, a physical exam, and imaging such as an MRI scan to see where the growth is and whether it involves a nerve. The diagnosis is usually confirmed by taking a small sample of the growth, or removing it, and examining the tissue under a microscope, sometimes with extra lab tests to tell it apart from other nerve-related lumps. Genetic testing is not usually the main way perineurioma is diagnosed, but it may be used in some cases if the doctor needs more information or wants to rule out a different condition.
Stages of Perineurioma
Perineurioma does not have defined progression stages. That is because it is usually a slow-growing tumor identified by what it is and where it is, rather than by a step-by-step pattern of worsening over time. Doctors usually start with a conversation about symptoms, such as a gradually enlarging lump or slowly increasing weakness, which can overlap with the early symptoms of perineurioma. Diagnosis is usually confirmed with imaging, often MRI, and a tissue sample examined under a microscope, while follow-up focuses on checking for growth, nerve-related symptoms, or return after treatment.
Outlook and prognosis
The outlook for people with perineurioma is generally excellent because most tumors are benign and grow slowly. After complete surgical removal, local control is usually very good, and recurrence is uncommon, although it can occur if the lesion is not fully excised. Intraneural perineurioma may leave persistent weakness, numbness, or muscle wasting depending on how much nerve function was affected before treatment, so recovery can be incomplete even when the tumor itself is controlled. Soft tissue perineurioma also usually behaves in an indolent way, with metastasis being exceptionally rare. Overall survival is expected to be normal in the vast majority of cases, and deaths from perineurioma are exceedingly rare. Long-term follow-up is sometimes advised, especially for tumors in difficult locations or when pathology shows atypical features.
Long-term effects
For many people, perineurioma has a good long-term outlook, especially because it is usually a benign growth and does not spread to distant parts of the body. The main long-term effects tend to come from where the tumor is located and whether it involves a nerve, so daily impact can range from barely noticeable to ongoing weakness or numbness in one area. In medical terms, these are sometimes called late effects or chronic symptoms. When people ask about the long-term effects of perineurioma, doctors usually focus on nerve function, symptom persistence, and the chance that the growth could come back after treatment.
If perineurioma grows within or around a nerve, numbness, tingling, or altered feeling can last over time. Some people continue to notice a patch of skin that feels less sensitive, even after treatment.
Many living with perineurioma may have lasting weakness in the affected arm, hand, leg, or foot if the tumor has disrupted nerve signals. This can show up in everyday life as trouble lifting the front of the foot, gripping objects, or doing fine hand movements.
Some perineuriomas stay painless, but others can cause ongoing aching, tenderness, or discomfort with movement or pressure. Long-term effects vary widely, and pain is often linked to the tumor's size, location, and whether nearby nerves are irritated.
After surgery, nerve-related symptoms may improve slowly over months rather than days. If the nerve was already significantly affected before treatment, some weakness or sensory change may remain long term.
How is it to live with Perineurioma?
Living with perineurioma often means dealing with a problem that grows quietly rather than dramatically: many people notice a slow, painless lump, while others, especially with intraneural perineurioma, develop gradually worsening weakness, numbness, or clumsiness in one arm or leg. In daily life, that can make walking, gripping objects, writing, buttoning clothes, or keeping up with work and exercise more tiring, although symptoms often stay localized instead of affecting the whole body. For family and others nearby, the biggest impact is usually practical and emotional, such as helping with appointments, adapting routines, and understanding that a condition described as benign can still interfere with comfort, mobility, and confidence.
Treatment and drugs
Perineurioma is usually treated based on where the growth is, how fast it is changing, and whether it is causing symptoms such as pain, numbness, weakness, or a visible lump. For many people, treatment begins with small daily steps, such as tracking symptoms and having repeat exams or imaging if the tumor seems stable and is not bothering nearby nerves or tissues. If perineurioma is causing problems or continues to grow, surgery is often the main treatment, with the goal of removing as much of the tumor as is safely possible while protecting nerve function as much as possible. In some cases, especially when a nerve is involved, treatment planning may include a nerve specialist, and recovery can involve physical or occupational therapy to help with strength and daily activities. Not every treatment works the same way for every person, so follow-up care is important to watch for return of the tumor and to guide the next steps if symptoms change.
Can you cure Perineurioma?
Perineurioma is usually not treated with medicine, but many people can be cured if the growth can be fully removed with surgery. If it is growing in or around an important nerve, surgery may not always be possible, and treatment may focus more on easing symptoms and protecting movement or feeling.
Non-drug treatment
Many people living with perineurioma do not need medicines, and day-to-day care often depends on where the growth is, whether it is causing weakness, numbness, or pain, and if it is changing over time. Non-drug treatment for perineurioma usually centers on careful monitoring, surgery when symptoms are progressing, and rehabilitation to protect movement and function. Not every approach works the same way, so care is often tailored to the nerve involved and how much the tumor affects daily life.
If a perineurioma is small and not causing major problems, doctors may recommend regular checkups and repeat scans instead of immediate treatment. This helps track any change in size, strength, or sensation over time.
Surgery may be considered when perineurioma is causing worsening weakness, bothersome pain, or clear loss of function. The goal is usually to remove as much of the tumor as is safely possible while protecting the nerve.
Physical therapy can help maintain strength, balance, and joint movement if a perineurioma affects an arm or leg. For many, treatment begins not at the pharmacy, but with guided exercises that make walking, climbing stairs, or using the hand easier.
Occupational therapy focuses on everyday tasks such as dressing, writing, gripping objects, or working at a keyboard. Therapists may suggest safer movement patterns, hand exercises, or simple tools that reduce strain.
Your genes may have an impact on how drugs work for you
Perineurioma is usually treated with monitoring or surgery rather than medicines, so genes are not known to play a big day-to-day role in how treatment works for most people living with this condition. If medication is used, it is usually for symptoms such as pain after a nerve problem or around treatment, and the usual differences in how people respond to pain medicines can still happen, but there are no well-established gene-based drug rules that are specific to perineurioma. In other words, genetic testing to choose medicine, sometimes called pharmacogenomics, is not a routine part of care for perineurioma at this time.
Pharmacological treatments
For many living with perineurioma, medicine is not the main treatment because these tumors are usually managed with monitoring or, in some cases, surgery. There is no standard drug that removes or cures a perineurioma, so medicines are mainly used to ease symptoms such as pain, tingling, or nerve irritation. If symptoms are mild, some people may not need medication at all.
Acetaminophen can help with mild pain linked to perineurioma, especially if the area feels sore or achy. It does not treat the tumor itself, but it may make day-to-day discomfort easier to manage.
Ibuprofen or naproxen may help if perineurioma causes pain with some swelling or irritation around nearby tissues. These drugs are used for symptom relief, and they may not help much if the pain is mainly coming from nerve damage.
Gabapentin or pregabalin may be used when pain feels burning, shooting, or electric, which can happen with nerve-related symptoms. Not everyone responds to the same medication in the same way, so the best pain medication for perineurioma can differ from one person to another.
Amitriptyline or duloxetine are sometimes prescribed in low doses for nerve pain, even when someone is not depressed. These medicines can be useful if perineurioma symptoms include ongoing tingling, hypersensitivity, or pain that disrupts sleep.
Genetic influences
Hearing that a tumor has a genetic link can make many living with perineurioma wonder about their family, too. In most cases, perineurioma does not seem to be an inherited condition and usually is not passed from parent to child. A change in a gene (mutation or variant) can sometimes affect health, and researchers have found gene changes in some perineuriomas, including changes involving TRAF7 or loss of genetic material on chromosome 22. These are usually somatic changes, which means they arise only in the tumor cells during life rather than being present in all of the body’s cells. That is why, when people ask whether perineurioma is hereditary, the answer is usually no, although doctors may look more closely if there are multiple nerve tumors or other unusual features.
Is Perineurioma genetic?
Genetics can matter in perineurioma, but it is usually linked to changes that arise in the affected tissue rather than changes inherited from a parent. Many people with perineurioma do not have a family history, and inherited risk is not usually a major factor.
Having a genetic risk is not necessarily a diagnosis
Genetic variants are a usual part of human biology and are widespread in the general population. Most do not directly affect health and are simply part of normal human variation. For many genes, having a variant tied to a condition suggests a possible link rather than a certain diagnosis, especially when several genes and environmental factors are involved. In some situations, though, one well-understood variant in a particular gene can be enough to confirm a diagnosis.
Pharmacogenetics—how genetics influence drug effects
For many people with perineurioma, treatment is shaped more by day-to-day symptoms such as pain, numbness, or weakness than by a medication plan, because medicines are not usually the main treatment. In most cases, doctors rely on careful monitoring or surgery if the tumor is affecting a nerve or getting in the way of movement or comfort. Genetics is only one factor, and in perineurioma, genetic findings are currently used more to support the diagnosis or tell it apart from other nerve tumors than to choose a drug. Researchers have found genetic changes in some perineurioma cells, but these changes do not yet point to a standard targeted medicine. If pain relief or other supportive medicines are needed, gene-related differences in drug response may still matter in a general way, but this is not specific to perineurioma itself. So when people ask about the role of genetics in treatment options for perineurioma, the short answer is that genetics may help doctors understand the tumor, but it rarely changes treatment choices at this time.
Interactions with other conditions
Perineurioma does not usually cause broad health problems throughout the body, but it can overlap in practical ways with other nerve, muscle, or mobility conditions because it may weaken part of an arm or leg. Someone might notice their symptoms flare when another condition is active, such as arthritis, a back problem, or diabetes-related nerve damage, which can make it harder to tell what is causing numbness, pain, or weakness. This matters because the early symptoms of perineurioma can look similar to more common problems like a pinched nerve or another benign nerve tumor, so doctors often need imaging and sometimes a biopsy to sort them apart. Unlike some other nerve tumors, perineurioma is not usually linked to common inherited tumor syndromes, so finding one does not automatically mean there is a broader genetic disease. If perineurioma affects walking, grip, or balance, it can also add to the day-to-day impact of other conditions that already limit movement. Talk with your doctor about how your conditions may influence each other, especially if symptoms are changing or treatment for another illness does not explain what you are feeling.
How genes can cause diseases
Humans have more than 20,000 genes, each carrying out one or a few specific functions in the body. One gene instructs the body to digest lactose from milk, another tells the body how to build strong bones and another prevents the body's cells from beginning to multiply uncontrollably and developing into cancer. As all of these genes combined are the building instructions for our body, a defect in one of these genes can have severe health consequences.
Through decades of genetic research, we know the genetic code of any healthy/functional human gene. We have also identified that in certain positions on a gene, some individuals may have a different genetic letter from the one you have. We call these hotspots "Genetic Variations" or "Variants" in short. In many cases, studies have been able to show that having the genetic letter "G" in the position makes you healthy, but having the letter "A" in the same position disrupts the gene function and causes a disease. Genopedia allows you to view these variants in genes and summarizes all that we know from scientific research, which genetic letters (Genotype) have good or bad consequences on your health or on your traits.
What other conditions can cause similar symptoms to Perineurioma?
Perineurioma can look a lot like other noncancerous growths that start in or around nerves, especially schwannoma and neurofibroma, and sometimes like a nerve that has healed with scar tissue after an injury. If it causes numbness, tingling, pain, or weakness instead of a noticeable lump, doctors may also think about more common nerve problems such as a pinched nerve, carpal tunnel syndrome, or a slipped disk in the neck or back. A soft tissue lump from something like a lipoma, which is a fatty growth, can also seem similar at first.
History
People living with perineurioma often reach the diagnosis only after a slow, puzzling stretch of symptoms, such as a small lump that has been there for months or years, or weakness and numbness that seem out of proportion to what can be seen from the outside. That slow course is one reason the condition took time to be clearly recognized in medicine. Earlier reports often grouped these growths with other nerve sheath tumors because they can look similar at first glance.
As medical science evolved, doctors began to notice that some tumors had a distinct pattern under the microscope and behaved differently from better-known nerve tumors. This helped separate perineurioma into its own category. Over time, specialists also recognized that perineurioma can show up in more than one way: some people have a soft-tissue form that appears as a painless mass, while others have a form that affects a nerve more directly and can cause weakness, tingling, or wasting in part of an arm or leg.
The history of perineurioma also reflects broader changes in how rare conditions are studied. Better imaging, more detailed lab staining, and improved pathology methods made it easier to identify these tumors more reliably and avoid confusion with look-alike conditions. In recent decades, awareness has grown, and that has helped doctors better understand the early symptoms of perineurioma, its usually slow growth, and its generally noncancerous nature.
Today, perineurioma is still considered uncommon, but it is much more clearly defined than it was in the past. That matters in everyday life because a more accurate diagnosis can guide treatment and reduce unnecessary worry. Many living with perineurioma are reassured to learn that although the name is unfamiliar, the condition has been steadily studied and is now better understood than it once was.