Overview

SNPs are specific locations in the DNA where genetic variations can occur. Every person has a unique composition of variations.

SNP rs2736100 is located on chromosome 5. The most common variation at this position is the C. People with other variations might have letter A instead.

Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation assembly is referred to as genotype. For SNP rs2736100 there are 3 currently known genotypes: A/C , C/C or A/A

Genome Browser

This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of SNP rs2736100. Explore more SNPs and their effects on the body by browsing left and right along the DNA strand.

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Mitochondrial DNAMitochondrial DNA
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Effects relating to rs2736100

Your genetic code influences you in many ways. This may be by either causing you to have a specific trait (eg. Eye colour) or your risk of developing a specific disease.

Each combination of genetic letters (called bases) is called a genotype for this specific SNP. Each Genotype can have a different effect on your body. The table below shows which genotype causes which traits or disease risks.

Current research shows 9 disease risks associated with rs2736100. The following table shows the relationship between genotype and .



Genotype AC

Effect Likelihood Level of evidenceResearch
Glioma
1.29x
Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot” (2010)

Text Extract:

Although TERT variants have not been previously reported to be associated with ovarian cancer, a recent meta-analysis of two GWAS identified another SNP in TERT, rs2736100, as significantly associated with gliomas (OR=1.27; P=1.501017) [21]

PMCID: PMCID2900295
Read on PMC
Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma. (2014)

Zhou, Peng, Wei, Li, Xia, Xiwei, Shao, Naiyuan, Qian, Xinyu, Yang, Yilin

Text Extract:

Overall, we found that TERT rs2736100 polymorphism was significantly associated with the risk of glioma (OR = 1.29, 95% CI 1.24-1.34, P < 0.001)

PMID: PMID24888789
Read on PubMed
Serous ovarian cancer
0.88x
Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot” (2010)

Text Extract:

We genotyped rs2736100 in the discovery samples and found a borderline, but inverse, association with serous ovarian cancer [OR=0.88 (0.771.01) P Trend=0.06]

PMCID: PMCID2900295
Read on PMC
Adenocarcinoma (ADC)
1.16x
Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia (2014)

Park, S. Lani, Fesinmeyer, Megan D., Timofeeva, Maria, Caberto, Christian P., Kocarnik, Jonathan M., Han, Younghun, Love, Shelly-Ann, Young, Alicia, Dumitrescu, Logan, Lin, Yi, Goodloe, Robert, Wilkens, Lynne R., Hindorff, Lucia, Fowke, Jay H., Carty, Cara, Buyske, Steven, Schumacher, Frederick R., Butler, Anne, Dilks, Holli, Deelman, Ewa, Cote, Michele L., Chen, Wei, Pande, Mala, Christiani, David C., Field, John K., Bickebӧller, Heike, Risch, Angela, Heinrich, Joachim, Brennan, Paul, Wang, Yufei, Eisen, Timothy, Houlston, Richard S., Thun, Michael, Albanes, Demetrius, Caporaso, Neil, Peters, Ulrike, North, Kari E., Heiss, Gerardo, Crawford, Dana C., Bush, William S., Haiman, Christopher A., Landi, Maria Teresa, Hung, Rayjean J., Kooperberg, Charles, Amos, Christopher I., Le Marchand, Loïc, Cheng, Iona

Text Extract:

Alternatively, the meta-analyzed result among these six studies when not conditioned on rs2736100 was similar to the main adenocarcinoma finding (OR = 1.16; P = 1.3107)

PMCID: PMCID3982896
Read on PMC
Atrial fibrillation (AF)
0.95x
Telomere Length and the Risk of Atrial Fibrillation: Insights into the Role of Biological versus Chronological Aging (2014)

Roberts, Jason D., Dewland, Thomas A., Longoria, James, Fitzpatrick, Annette L., Ziv, Elad, Hu, Donglei, Lin, Jue, Glidden, David V., Psaty, Bruce M., Burchard, Esteban G., Blackburn, Elizabeth H., Olgin, Jeffrey E., Heckbert, Susan R., Marcus, Gregory M.

Text Extract:

No association was observed between the TERT rs2736100 SNP and incident AF (adjusted HR: 0.95; 95% CI: 0.881.04, p=0.265)

PMCID: PMCID4294941
Read on PMC
Papillary thyroid carcinoma (PTC)
1.39x
Functional evaluation of TERT-CLPTM1L genetic variants associated with susceptibility of papillary thyroid carcinoma (2016)

Ge, Minghua, Shi, Meng, An, Changming, Yang, Wenjun, Nie, Xilin, Zhang, Jian, Lv, Zheng, Li, Jinliang, Zhou, Liqing, Du, Zhongli, Yang, Ming

Text Extract:

In details, rs2736100 genetic variant was associated with significantly elevated PTC risk (allelic OR=1.39, 95% CI=1.161.66, P=7.0106) (Table 2)

PMCID: PMCID4869017
Read on PMC
Hepatocellular carcinoma (HCC)
0.74x
The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma (2017)

Yuan, Xiaotian, Cheng, Guanghui, Yu, Jingya, Zheng, Shunzhen, Sun, Chao, Sun, Qing, Li, Kailin, Lin, Zhaomin, Liu, Tiantian, Li, Ping, Xu, Yiteng, Kong, Feng, Bjorkholm, Magnus, Xu, Dawei

Text Extract:

However, the rs2736100_CC genotype was significantly lower in HCC patients than in healthy controls (OR: 0.544, 95% CI: 0.3200.925, P = 0.034) (Table 2)

PMCID: PMCID5410290
Read on PMC
Chronic widespread pain (CWP)
0.84x
NAF1 rs4691896 Is Significantly Associated with Coal Workers’ Pneumoconiosis in a Chinese Han Population: A Case-Control Study

Yuan, Baojun, Wen, Xiaoting, Li, Liubing, Li, Yongzhe, Li, Chao, Li, Baolin, Yuan, Wei, Cui, Liufu

Text Extract:

The C allele of rs2736100 from TERT showed a lower allele frequency in the patients with CWP than in the healthy subjects (38.4% vs. 42.7%, OR: 0.84, 95% CI: 0.720.98, P=0.04)

PMCID: PMCID7197226
Read on PMC
Pulmonary fibrosis (PF)
1.50x
Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden (2022)

Jönsson, Elias, Ljung, Lotta, Norrman, Eva, Freyhult, Eva, Ärlestig, Lisbeth, Dahlqvist, Johanna, Rantapää-Dahlqvist, Solbritt

Text Extract:

The SNP rs2736100 (TERT gene locus) was associated with the risk of PF after adjustments [OR 1.5 (95% CI 1.0, 2.2), adjusted P-value=0.046, q-value=0.15] (Table 2b)

PMCID: PMCID8889303
Read on PMC
Prostate cancer (PCA)
0.81x
Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness. (2016)

Wu, Dapeng, Yu, Hongjie, Sun, Jielin, Qi, Jun, Liu, Qiang, Li, Ruipeng, Zheng, Siqun Lily, Xu, Jianfeng, Kang, Jian

Text Extract:

It was observed that the C allele of the TERT intron 2 SNP (rs2736100) was significantly associated with reduced risk of PCa aggressiveness [odds ratio (OR)=0.81; 95% confidence interval (CI): 0.66-0.99; P=0.037]

PMID: PMID25738283
Read on PubMed
Legend:
Increased probability
Decreased probability
No known effect

Genotype CC

Effect Likelihood Level of evidenceResearch
Glioma
1.00x
Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot” (2010)

Text Extract:

Although TERT variants have not been previously reported to be associated with ovarian cancer, a recent meta-analysis of two GWAS identified another SNP in TERT, rs2736100, as significantly associated with gliomas (OR=1.27; P=1.501017) [21]

PMCID: PMCID2900295
Read on PMC
Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma. (2014)

Zhou, Peng, Wei, Li, Xia, Xiwei, Shao, Naiyuan, Qian, Xinyu, Yang, Yilin

Text Extract:

Overall, we found that TERT rs2736100 polymorphism was significantly associated with the risk of glioma (OR = 1.29, 95% CI 1.24-1.34, P < 0.001)

PMID: PMID24888789
Read on PubMed
Serous ovarian cancer
1.00x
Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot” (2010)

Text Extract:

We genotyped rs2736100 in the discovery samples and found a borderline, but inverse, association with serous ovarian cancer [OR=0.88 (0.771.01) P Trend=0.06]

PMCID: PMCID2900295
Read on PMC
Adenocarcinoma (ADC)
1.00x
Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia (2014)

Park, S. Lani, Fesinmeyer, Megan D., Timofeeva, Maria, Caberto, Christian P., Kocarnik, Jonathan M., Han, Younghun, Love, Shelly-Ann, Young, Alicia, Dumitrescu, Logan, Lin, Yi, Goodloe, Robert, Wilkens, Lynne R., Hindorff, Lucia, Fowke, Jay H., Carty, Cara, Buyske, Steven, Schumacher, Frederick R., Butler, Anne, Dilks, Holli, Deelman, Ewa, Cote, Michele L., Chen, Wei, Pande, Mala, Christiani, David C., Field, John K., Bickebӧller, Heike, Risch, Angela, Heinrich, Joachim, Brennan, Paul, Wang, Yufei, Eisen, Timothy, Houlston, Richard S., Thun, Michael, Albanes, Demetrius, Caporaso, Neil, Peters, Ulrike, North, Kari E., Heiss, Gerardo, Crawford, Dana C., Bush, William S., Haiman, Christopher A., Landi, Maria Teresa, Hung, Rayjean J., Kooperberg, Charles, Amos, Christopher I., Le Marchand, Loïc, Cheng, Iona

Text Extract:

Alternatively, the meta-analyzed result among these six studies when not conditioned on rs2736100 was similar to the main adenocarcinoma finding (OR = 1.16; P = 1.3107)

PMCID: PMCID3982896
Read on PMC
Atrial fibrillation (AF)
1.00x
Telomere Length and the Risk of Atrial Fibrillation: Insights into the Role of Biological versus Chronological Aging (2014)

Roberts, Jason D., Dewland, Thomas A., Longoria, James, Fitzpatrick, Annette L., Ziv, Elad, Hu, Donglei, Lin, Jue, Glidden, David V., Psaty, Bruce M., Burchard, Esteban G., Blackburn, Elizabeth H., Olgin, Jeffrey E., Heckbert, Susan R., Marcus, Gregory M.

Text Extract:

No association was observed between the TERT rs2736100 SNP and incident AF (adjusted HR: 0.95; 95% CI: 0.881.04, p=0.265)

PMCID: PMCID4294941
Read on PMC
Papillary thyroid carcinoma (PTC)
1.00x
Functional evaluation of TERT-CLPTM1L genetic variants associated with susceptibility of papillary thyroid carcinoma (2016)

Ge, Minghua, Shi, Meng, An, Changming, Yang, Wenjun, Nie, Xilin, Zhang, Jian, Lv, Zheng, Li, Jinliang, Zhou, Liqing, Du, Zhongli, Yang, Ming

Text Extract:

In details, rs2736100 genetic variant was associated with significantly elevated PTC risk (allelic OR=1.39, 95% CI=1.161.66, P=7.0106) (Table 2)

PMCID: PMCID4869017
Read on PMC
Hepatocellular carcinoma (HCC)
0.54x
The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma (2017)

Yuan, Xiaotian, Cheng, Guanghui, Yu, Jingya, Zheng, Shunzhen, Sun, Chao, Sun, Qing, Li, Kailin, Lin, Zhaomin, Liu, Tiantian, Li, Ping, Xu, Yiteng, Kong, Feng, Bjorkholm, Magnus, Xu, Dawei

Text Extract:

However, the rs2736100_CC genotype was significantly lower in HCC patients than in healthy controls (OR: 0.544, 95% CI: 0.3200.925, P = 0.034) (Table 2)

PMCID: PMCID5410290
Read on PMC
Chronic widespread pain (CWP)
0.71x
NAF1 rs4691896 Is Significantly Associated with Coal Workers’ Pneumoconiosis in a Chinese Han Population: A Case-Control Study

Yuan, Baojun, Wen, Xiaoting, Li, Liubing, Li, Yongzhe, Li, Chao, Li, Baolin, Yuan, Wei, Cui, Liufu

Text Extract:

The C allele of rs2736100 from TERT showed a lower allele frequency in the patients with CWP than in the healthy subjects (38.4% vs. 42.7%, OR: 0.84, 95% CI: 0.720.98, P=0.04)

PMCID: PMCID7197226
Read on PMC
Pulmonary fibrosis (PF)
1.00x
Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden (2022)

Jönsson, Elias, Ljung, Lotta, Norrman, Eva, Freyhult, Eva, Ärlestig, Lisbeth, Dahlqvist, Johanna, Rantapää-Dahlqvist, Solbritt

Text Extract:

The SNP rs2736100 (TERT gene locus) was associated with the risk of PF after adjustments [OR 1.5 (95% CI 1.0, 2.2), adjusted P-value=0.046, q-value=0.15] (Table 2b)

PMCID: PMCID8889303
Read on PMC
Prostate cancer (PCA)
0.66x
Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness. (2016)

Wu, Dapeng, Yu, Hongjie, Sun, Jielin, Qi, Jun, Liu, Qiang, Li, Ruipeng, Zheng, Siqun Lily, Xu, Jianfeng, Kang, Jian

Text Extract:

It was observed that the C allele of the TERT intron 2 SNP (rs2736100) was significantly associated with reduced risk of PCa aggressiveness [odds ratio (OR)=0.81; 95% confidence interval (CI): 0.66-0.99; P=0.037]

PMID: PMID25738283
Read on PubMed
Legend:
Increased probability
Decreased probability
No known effect

Genotype AA

Effect Likelihood Level of evidenceResearch
Glioma
1.58x
Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot” (2010)

Text Extract:

Although TERT variants have not been previously reported to be associated with ovarian cancer, a recent meta-analysis of two GWAS identified another SNP in TERT, rs2736100, as significantly associated with gliomas (OR=1.27; P=1.501017) [21]

PMCID: PMCID2900295
Read on PMC
Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma. (2014)

Zhou, Peng, Wei, Li, Xia, Xiwei, Shao, Naiyuan, Qian, Xinyu, Yang, Yilin

Text Extract:

Overall, we found that TERT rs2736100 polymorphism was significantly associated with the risk of glioma (OR = 1.29, 95% CI 1.24-1.34, P < 0.001)

PMID: PMID24888789
Read on PubMed
Serous ovarian cancer
0.77x
Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot” (2010)

Text Extract:

We genotyped rs2736100 in the discovery samples and found a borderline, but inverse, association with serous ovarian cancer [OR=0.88 (0.771.01) P Trend=0.06]

PMCID: PMCID2900295
Read on PMC
Adenocarcinoma (ADC)
1.32x
Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia (2014)

Park, S. Lani, Fesinmeyer, Megan D., Timofeeva, Maria, Caberto, Christian P., Kocarnik, Jonathan M., Han, Younghun, Love, Shelly-Ann, Young, Alicia, Dumitrescu, Logan, Lin, Yi, Goodloe, Robert, Wilkens, Lynne R., Hindorff, Lucia, Fowke, Jay H., Carty, Cara, Buyske, Steven, Schumacher, Frederick R., Butler, Anne, Dilks, Holli, Deelman, Ewa, Cote, Michele L., Chen, Wei, Pande, Mala, Christiani, David C., Field, John K., Bickebӧller, Heike, Risch, Angela, Heinrich, Joachim, Brennan, Paul, Wang, Yufei, Eisen, Timothy, Houlston, Richard S., Thun, Michael, Albanes, Demetrius, Caporaso, Neil, Peters, Ulrike, North, Kari E., Heiss, Gerardo, Crawford, Dana C., Bush, William S., Haiman, Christopher A., Landi, Maria Teresa, Hung, Rayjean J., Kooperberg, Charles, Amos, Christopher I., Le Marchand, Loïc, Cheng, Iona

Text Extract:

Alternatively, the meta-analyzed result among these six studies when not conditioned on rs2736100 was similar to the main adenocarcinoma finding (OR = 1.16; P = 1.3107)

PMCID: PMCID3982896
Read on PMC
Atrial fibrillation (AF)
0.90x
Telomere Length and the Risk of Atrial Fibrillation: Insights into the Role of Biological versus Chronological Aging (2014)

Roberts, Jason D., Dewland, Thomas A., Longoria, James, Fitzpatrick, Annette L., Ziv, Elad, Hu, Donglei, Lin, Jue, Glidden, David V., Psaty, Bruce M., Burchard, Esteban G., Blackburn, Elizabeth H., Olgin, Jeffrey E., Heckbert, Susan R., Marcus, Gregory M.

Text Extract:

No association was observed between the TERT rs2736100 SNP and incident AF (adjusted HR: 0.95; 95% CI: 0.881.04, p=0.265)

PMCID: PMCID4294941
Read on PMC
Papillary thyroid carcinoma (PTC)
1.78x
Functional evaluation of TERT-CLPTM1L genetic variants associated with susceptibility of papillary thyroid carcinoma (2016)

Ge, Minghua, Shi, Meng, An, Changming, Yang, Wenjun, Nie, Xilin, Zhang, Jian, Lv, Zheng, Li, Jinliang, Zhou, Liqing, Du, Zhongli, Yang, Ming

Text Extract:

In details, rs2736100 genetic variant was associated with significantly elevated PTC risk (allelic OR=1.39, 95% CI=1.161.66, P=7.0106) (Table 2)

PMCID: PMCID4869017
Read on PMC
Hepatocellular carcinoma (HCC)
1.00x
The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma (2017)

Yuan, Xiaotian, Cheng, Guanghui, Yu, Jingya, Zheng, Shunzhen, Sun, Chao, Sun, Qing, Li, Kailin, Lin, Zhaomin, Liu, Tiantian, Li, Ping, Xu, Yiteng, Kong, Feng, Bjorkholm, Magnus, Xu, Dawei

Text Extract:

However, the rs2736100_CC genotype was significantly lower in HCC patients than in healthy controls (OR: 0.544, 95% CI: 0.3200.925, P = 0.034) (Table 2)

PMCID: PMCID5410290
Read on PMC
Chronic widespread pain (CWP)
1.00x
NAF1 rs4691896 Is Significantly Associated with Coal Workers’ Pneumoconiosis in a Chinese Han Population: A Case-Control Study

Yuan, Baojun, Wen, Xiaoting, Li, Liubing, Li, Yongzhe, Li, Chao, Li, Baolin, Yuan, Wei, Cui, Liufu

Text Extract:

The C allele of rs2736100 from TERT showed a lower allele frequency in the patients with CWP than in the healthy subjects (38.4% vs. 42.7%, OR: 0.84, 95% CI: 0.720.98, P=0.04)

PMCID: PMCID7197226
Read on PMC
Pulmonary fibrosis (PF)
2.00x
Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden (2022)

Jönsson, Elias, Ljung, Lotta, Norrman, Eva, Freyhult, Eva, Ärlestig, Lisbeth, Dahlqvist, Johanna, Rantapää-Dahlqvist, Solbritt

Text Extract:

The SNP rs2736100 (TERT gene locus) was associated with the risk of PF after adjustments [OR 1.5 (95% CI 1.0, 2.2), adjusted P-value=0.046, q-value=0.15] (Table 2b)

PMCID: PMCID8889303
Read on PMC
Prostate cancer (PCA)
1.00x
Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness. (2016)

Wu, Dapeng, Yu, Hongjie, Sun, Jielin, Qi, Jun, Liu, Qiang, Li, Ruipeng, Zheng, Siqun Lily, Xu, Jianfeng, Kang, Jian

Text Extract:

It was observed that the C allele of the TERT intron 2 SNP (rs2736100) was significantly associated with reduced risk of PCa aggressiveness [odds ratio (OR)=0.81; 95% confidence interval (CI): 0.66-0.99; P=0.037]

PMID: PMID25738283
Read on PubMed
Legend:
Increased probability
Decreased probability
No known effect

Distribution

Knowing your genome can actually tell you a lot about your ancestors.

The prevalence of the different genotypes is based on the native inhabitants of a region. In the map below you see how common each genotype is in the native inhabitants of those regions. Since genetic material is passed down form generation to generation, your DNA shows traces of the geographical origins of your ancestors.

This data is based on “The 1000 Genomes Project” which established one of the most detailed overviews of human genetic variations across the globe. The regions are broadly categorized into five continental groups: Africa, America, Europe, South Asia and East Asia. All continental groups together display the global prevalence. Click through the regions, to learn more about the local prevalence of the possible genotypes.

At present, there is no distribution data available for SNP rs2736100.

Studies and sources

All of the resources below examine SNP rs2736100

Genotype AC

Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma. (2014)

Zhou, Peng, Wei, Li, Xia, Xiwei, Shao, Naiyuan, Qian, Xinyu, Yang, Yilin

PMID: PMID24888789
Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia (2014)

Park, S. Lani, Fesinmeyer, Megan D., Timofeeva, Maria, Caberto, Christian P., Kocarnik, Jonathan M., Han, Younghun, Love, Shelly-Ann, Young, Alicia, Dumitrescu, Logan, Lin, Yi, Goodloe, Robert, Wilkens, Lynne R., Hindorff, Lucia, Fowke, Jay H., Carty, Cara, Buyske, Steven, Schumacher, Frederick R., Butler, Anne, Dilks, Holli, Deelman, Ewa, Cote, Michele L., Chen, Wei, Pande, Mala, Christiani, David C., Field, John K., Bickebӧller, Heike, Risch, Angela, Heinrich, Joachim, Brennan, Paul, Wang, Yufei, Eisen, Timothy, Houlston, Richard S., Thun, Michael, Albanes, Demetrius, Caporaso, Neil, Peters, Ulrike, North, Kari E., Heiss, Gerardo, Crawford, Dana C., Bush, William S., Haiman, Christopher A., Landi, Maria Teresa, Hung, Rayjean J., Kooperberg, Charles, Amos, Christopher I., Le Marchand, Loïc, Cheng, Iona

PMCID: PMCID3982896
Telomere Length and the Risk of Atrial Fibrillation: Insights into the Role of Biological versus Chronological Aging (2014)

Roberts, Jason D., Dewland, Thomas A., Longoria, James, Fitzpatrick, Annette L., Ziv, Elad, Hu, Donglei, Lin, Jue, Glidden, David V., Psaty, Bruce M., Burchard, Esteban G., Blackburn, Elizabeth H., Olgin, Jeffrey E., Heckbert, Susan R., Marcus, Gregory M.

PMCID: PMCID4294941
Functional evaluation of TERT-CLPTM1L genetic variants associated with susceptibility of papillary thyroid carcinoma (2016)

Ge, Minghua, Shi, Meng, An, Changming, Yang, Wenjun, Nie, Xilin, Zhang, Jian, Lv, Zheng, Li, Jinliang, Zhou, Liqing, Du, Zhongli, Yang, Ming

PMCID: PMCID4869017
The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma (2017)

Yuan, Xiaotian, Cheng, Guanghui, Yu, Jingya, Zheng, Shunzhen, Sun, Chao, Sun, Qing, Li, Kailin, Lin, Zhaomin, Liu, Tiantian, Li, Ping, Xu, Yiteng, Kong, Feng, Bjorkholm, Magnus, Xu, Dawei

PMCID: PMCID5410290
NAF1 rs4691896 Is Significantly Associated with Coal Workers’ Pneumoconiosis in a Chinese Han Population: A Case-Control Study

Yuan, Baojun, Wen, Xiaoting, Li, Liubing, Li, Yongzhe, Li, Chao, Li, Baolin, Yuan, Wei, Cui, Liufu

PMCID: PMCID7197226
Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden (2022)

Jönsson, Elias, Ljung, Lotta, Norrman, Eva, Freyhult, Eva, Ärlestig, Lisbeth, Dahlqvist, Johanna, Rantapää-Dahlqvist, Solbritt

PMCID: PMCID8889303
Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness. (2016)

Wu, Dapeng, Yu, Hongjie, Sun, Jielin, Qi, Jun, Liu, Qiang, Li, Ruipeng, Zheng, Siqun Lily, Xu, Jianfeng, Kang, Jian

PMID: PMID25738283

Genotype CC

Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma. (2014)

Zhou, Peng, Wei, Li, Xia, Xiwei, Shao, Naiyuan, Qian, Xinyu, Yang, Yilin

PMID: PMID24888789
Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia (2014)

Park, S. Lani, Fesinmeyer, Megan D., Timofeeva, Maria, Caberto, Christian P., Kocarnik, Jonathan M., Han, Younghun, Love, Shelly-Ann, Young, Alicia, Dumitrescu, Logan, Lin, Yi, Goodloe, Robert, Wilkens, Lynne R., Hindorff, Lucia, Fowke, Jay H., Carty, Cara, Buyske, Steven, Schumacher, Frederick R., Butler, Anne, Dilks, Holli, Deelman, Ewa, Cote, Michele L., Chen, Wei, Pande, Mala, Christiani, David C., Field, John K., Bickebӧller, Heike, Risch, Angela, Heinrich, Joachim, Brennan, Paul, Wang, Yufei, Eisen, Timothy, Houlston, Richard S., Thun, Michael, Albanes, Demetrius, Caporaso, Neil, Peters, Ulrike, North, Kari E., Heiss, Gerardo, Crawford, Dana C., Bush, William S., Haiman, Christopher A., Landi, Maria Teresa, Hung, Rayjean J., Kooperberg, Charles, Amos, Christopher I., Le Marchand, Loïc, Cheng, Iona

PMCID: PMCID3982896
Telomere Length and the Risk of Atrial Fibrillation: Insights into the Role of Biological versus Chronological Aging (2014)

Roberts, Jason D., Dewland, Thomas A., Longoria, James, Fitzpatrick, Annette L., Ziv, Elad, Hu, Donglei, Lin, Jue, Glidden, David V., Psaty, Bruce M., Burchard, Esteban G., Blackburn, Elizabeth H., Olgin, Jeffrey E., Heckbert, Susan R., Marcus, Gregory M.

PMCID: PMCID4294941
Functional evaluation of TERT-CLPTM1L genetic variants associated with susceptibility of papillary thyroid carcinoma (2016)

Ge, Minghua, Shi, Meng, An, Changming, Yang, Wenjun, Nie, Xilin, Zhang, Jian, Lv, Zheng, Li, Jinliang, Zhou, Liqing, Du, Zhongli, Yang, Ming

PMCID: PMCID4869017
The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma (2017)

Yuan, Xiaotian, Cheng, Guanghui, Yu, Jingya, Zheng, Shunzhen, Sun, Chao, Sun, Qing, Li, Kailin, Lin, Zhaomin, Liu, Tiantian, Li, Ping, Xu, Yiteng, Kong, Feng, Bjorkholm, Magnus, Xu, Dawei

PMCID: PMCID5410290
NAF1 rs4691896 Is Significantly Associated with Coal Workers’ Pneumoconiosis in a Chinese Han Population: A Case-Control Study

Yuan, Baojun, Wen, Xiaoting, Li, Liubing, Li, Yongzhe, Li, Chao, Li, Baolin, Yuan, Wei, Cui, Liufu

PMCID: PMCID7197226
Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden (2022)

Jönsson, Elias, Ljung, Lotta, Norrman, Eva, Freyhult, Eva, Ärlestig, Lisbeth, Dahlqvist, Johanna, Rantapää-Dahlqvist, Solbritt

PMCID: PMCID8889303
Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness. (2016)

Wu, Dapeng, Yu, Hongjie, Sun, Jielin, Qi, Jun, Liu, Qiang, Li, Ruipeng, Zheng, Siqun Lily, Xu, Jianfeng, Kang, Jian

PMID: PMID25738283

Genotype AA

Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma. (2014)

Zhou, Peng, Wei, Li, Xia, Xiwei, Shao, Naiyuan, Qian, Xinyu, Yang, Yilin

PMID: PMID24888789
Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia (2014)

Park, S. Lani, Fesinmeyer, Megan D., Timofeeva, Maria, Caberto, Christian P., Kocarnik, Jonathan M., Han, Younghun, Love, Shelly-Ann, Young, Alicia, Dumitrescu, Logan, Lin, Yi, Goodloe, Robert, Wilkens, Lynne R., Hindorff, Lucia, Fowke, Jay H., Carty, Cara, Buyske, Steven, Schumacher, Frederick R., Butler, Anne, Dilks, Holli, Deelman, Ewa, Cote, Michele L., Chen, Wei, Pande, Mala, Christiani, David C., Field, John K., Bickebӧller, Heike, Risch, Angela, Heinrich, Joachim, Brennan, Paul, Wang, Yufei, Eisen, Timothy, Houlston, Richard S., Thun, Michael, Albanes, Demetrius, Caporaso, Neil, Peters, Ulrike, North, Kari E., Heiss, Gerardo, Crawford, Dana C., Bush, William S., Haiman, Christopher A., Landi, Maria Teresa, Hung, Rayjean J., Kooperberg, Charles, Amos, Christopher I., Le Marchand, Loïc, Cheng, Iona

PMCID: PMCID3982896
Telomere Length and the Risk of Atrial Fibrillation: Insights into the Role of Biological versus Chronological Aging (2014)

Roberts, Jason D., Dewland, Thomas A., Longoria, James, Fitzpatrick, Annette L., Ziv, Elad, Hu, Donglei, Lin, Jue, Glidden, David V., Psaty, Bruce M., Burchard, Esteban G., Blackburn, Elizabeth H., Olgin, Jeffrey E., Heckbert, Susan R., Marcus, Gregory M.

PMCID: PMCID4294941
Functional evaluation of TERT-CLPTM1L genetic variants associated with susceptibility of papillary thyroid carcinoma (2016)

Ge, Minghua, Shi, Meng, An, Changming, Yang, Wenjun, Nie, Xilin, Zhang, Jian, Lv, Zheng, Li, Jinliang, Zhou, Liqing, Du, Zhongli, Yang, Ming

PMCID: PMCID4869017
The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma (2017)

Yuan, Xiaotian, Cheng, Guanghui, Yu, Jingya, Zheng, Shunzhen, Sun, Chao, Sun, Qing, Li, Kailin, Lin, Zhaomin, Liu, Tiantian, Li, Ping, Xu, Yiteng, Kong, Feng, Bjorkholm, Magnus, Xu, Dawei

PMCID: PMCID5410290
NAF1 rs4691896 Is Significantly Associated with Coal Workers’ Pneumoconiosis in a Chinese Han Population: A Case-Control Study

Yuan, Baojun, Wen, Xiaoting, Li, Liubing, Li, Yongzhe, Li, Chao, Li, Baolin, Yuan, Wei, Cui, Liufu

PMCID: PMCID7197226
Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden (2022)

Jönsson, Elias, Ljung, Lotta, Norrman, Eva, Freyhult, Eva, Ärlestig, Lisbeth, Dahlqvist, Johanna, Rantapää-Dahlqvist, Solbritt

PMCID: PMCID8889303
Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness. (2016)

Wu, Dapeng, Yu, Hongjie, Sun, Jielin, Qi, Jun, Liu, Qiang, Li, Ruipeng, Zheng, Siqun Lily, Xu, Jianfeng, Kang, Jian

PMID: PMID25738283