Mutations are changes in genes and genetic variations are differences in the DNA among people. Variants are tiny changes in just one piece of the DNA while haplotypes are groups of these changes that usually come together.
Overview
rs2660753 is a genetic variant.
This variant is located on chromosome 3. The variations at position 87061524 are the genetic letters C/C, T/T, C/T
Since humans have each twice (one from each parent), these letter-variations occur on both chromosomes. People can have the same or different letters on both chromosomes. Every person's individual variation combination is referred to as genotype. For variant rs2660753 there are 3 currently known genotypes : C/C, T/T or C/T
Short Overview
Variant Location
rs2660753 is located on gene in chromsome 3. Use the genome browser to explore the location of rs2660753 and its genetic neighbourhood.
Conditions & Traits
rs2660753 affects the following conditions and traits:
There are currently 0 conditions and 0 traits associated with rs2660753.
Pathogenicity
rs2660753 affects the following conditions:
There are currently 0 conditions associated with rs2660753.
Pharmacogenetics
We do not have any data that links rs2660753 to any drugs.
Genome Browser
This interactive browser visualizes what no human can see with the naked eye - our DNA. From a down to a specific position on a . The position you are looking at here is the exact location of variant rs. Explore more variants and their effects on the body by browsing left and right along the DNA strand.
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Genotype Distribution
Knowing your genome can actually tell you a lot about your ancestors.
The prevalence of the different genotypes is based on the native inhabitants of a region. In the map below you see how common each genotype is in the native inhabitants of those regions. Since genetic material is passed down form generation to generation, your DNA shows traces of the geographical origins of your ancestors.
This data is based on “The 1000 Genomes Project” which established one of the most detailed overviews of human genetic variations across the globe. The regions are broadly categorized into five continental groups: Africa, America, Europe, South Asia and East Asia. All continental groups together display the global prevalence. Click through the regions, to learn more about the local prevalence of the possible genotypes.
At present, there is no distribution data available for SNP 2660753. 2660753.
The Genotype Distribution in the selected area is:
Legend:
Included regions
Excluded regions
no-data
Conditions & Traits of rs2660753
Current research shows 0 conditions and 0 traits.
Conditions
0Studies and Sources
All of the resources below examine variant rs2660753
Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions (10/1/15)
Ying Han, Dennis J. Hazelett, Fredrik Wiklund, Fredrick R. Schumacher, Daniel O. Stram, Sonja I. Berndt, Zhaoming Wang, Kristin A. Rand, Robert N. Hoover, Mitchell J. Machiela, Merideth Yeager, Laurie Burdette, Charles C. Chung, Amy Hutchinson, Kai Yu, Jianfeng Xu, Ruth C. Travis, Timothy J. Key, Afshan Siddiq, Federico Canzian, Atsushi Takahashi, Michiaki Kubo, Janet L. Stanford, Suzanne Kolb, Susan M. Gapstur, W. Ryan Diver, Victoria L. Stevens, Sara S. Strom, Curtis A. Pettaway, Ali Amin Al Olama, Zsofia Kote-Jarai, Rosalind A. Eeles, Edward D. Yeboah, Yao Tettey, Richard B. Biritwum, Andrew A. Adjei, Evelyn Tay, Ann Truelove, Shelley Niwa, Anand P. Chokkalingam, William B. Isaacs, Constance Chen, Sara Lindstrom, Loic Le Marchand, Edward L. Giovannucci, Mark Pomerantz, Henry Long, Fugen Li, Jing Ma, Meir Stampfer, Esther M. John, Sue A. Ingles, Rick A. Kittles, Adam B. Murphy, William J. Blot, Lisa B. Signorello, Wei Zheng, Demetrius Albanes, Jarmo Virtamo, Stephanie Weinstein, Barbara Nemesure, John Carpten, M. Cristina Leske, Suh-Yuh Wu, Anselm J. M. Hennis, Benjamin A. Rybicki, Christine Neslund-Dudas, Ann W. Hsing, Lisa Chu, Phyllis J. Goodman, Eric A. Klein, S. Lilly Zheng, John S. Witte, Graham Casey, Elio Riboli, Qiyuan Li, Matthew L. Freedman, David J. Hunter, Henrik Gronberg, Michael B. Cook, Hidewaki Nakagawa, Peter Kraft, Stephen J. Chanock, Douglas F. Easton, Brian E. Henderson, Gerhard A. Coetzee, David V. Conti, Christopher A. Haiman
PMC: 4572069
The Cumulative Effect of Gene-Gene and Gene-Environment Interactions on the Risk of Prostate Cancer in Chinese Men (1/27/16)
Ming Liu, Xiaohong Shi, Fan Yang, Jianye Wang, Yong Xu, Dong Wei, Kuo Yang, Yaoguang Zhang, Xin Wang, Siying Liang, Xin Chen, Liang Sun, Xiaoquan Zhu, Chengxiao Zhao, Ling Zhu, Lei Tang, Chenguang Zheng, Ze Yang
PMC: 4772182
Association of prostate cancer risk variants with TMPRSS2:ERG status: evidence for distinct molecular subtypes (4/20/16)
Kathryn L. Penney, Andreas Pettersson, Irene M. Shui, Rebecca E. Graff, Peter Kraft, Rosina T. Lis, Howard D. Sesso, Massimo Loda, Lorelei A. Mucci
PMC: 4873420